Assessment of the RTS,S/AS01 malaria vaccine.

V S Moorthy, R D Newman, P Duclos, J M Okwo-Bele, P G Smith

Registry-linked trialAbstract readComment

In one paragraph

Article in The Lancet. Infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02206451 (Assessing Human-to-Mosquito Transmission in Volunteers Participating in Malaria Vaccine Candidate Trials in Don), which is not on this map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02206451 completednot on this mapstarted 2014, after this paper: background citation

Assessing Human-to-Mosquito Transmission in Volunteers Participating in Malaria Vaccine Candidate Trials in Don(SqrRoot)(Copyright)gu(SqrRoot)(Copyright)Bougou Mali

TypeobservationalSponsorNational Institute of Allergy and Infectious Diseases (NIAID)Ran2014 to 2014Enrolled87ConditionsMalaria

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

Can combination prevention strategies reduce HIV transmission in generalized epidemic settings in Africa? The HPTN 071 (PopART) study plan in South Africa and Zambia.Journal of acquired immune deficiency syndromes (1999) · 2013
Trial
Malaria Vaccines and Global Equity: A Scoping Review of Current Progress and Future Directions.Biomedicines · 2025
Review
An ImmunoPEGliposome for Targeted Antimalarial Combination Therapy at the Nanoscale.Pharmaceutics · 2019
Article
Malaria vaccine research and development: the role of the WHO MALVAC committee.Malaria journal · 2013
Review

4 · The record

Corrections and comments

Comment on
Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data.2013

5 · Who and what money

Authors and funding

5 authors.

V S MoorthyDepartment of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland. moorthyv@who.int

R D Newman

P Duclos

J M Okwo-Bele

P G Smith

Funding

Medical Research Council G1002624Medical Research Council MR/K012126/1

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adjuvants, ImmunologicFemaleHumansMalaria, FalciparumMalaria VaccinesMalePlasmodium falciparumAdjuvants, ImmunologicMalaria Vaccines

Identifiers

PMID23454165

DOI10.1016/S1473-3099(13)70047-1

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

NCT02206451ClinicalTrials.gov

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.