Evidence map›Paper›PMID 23454038›Full record

ArticleThe Canadian journal of cardiology2013

The impact of cardiovascular risk-factor profiles on blood pressure control rates in adults from Canada and the United States.

Finlay A McAlister, Cynthia Robitaille, Cathleen Gillespie, Keming Yuan, Deepa P Rao, Steven Grover, Sulan Dai, Helen Johansen, Michel Joffres, Fleetwood Loustalot and 1 more

Abstract readComparative Study
In one paragraph

Article in The Canadian journal of cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE): 2014 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014
    Guideline
  2. Ups and downs of hypertension control in Canada: critical factors and lessons learned.Revista panamericana de salud publica = Pan American journal of public health · 2022
    Article
  3. Secular trends of ischaemic heart disease, stroke, and dementia in high-income countries from 1990 to 2017: the Global Burden of Disease Study 2017.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  4. Article
  5. Article
  6. Take urgent action diagnosing, treating, and controlling hypertension in older women.Canadian family physician Medecin de famille canadien · 2020
    Article
  7. Article
  8. São Paulo call to action for the prevention and control of high blood pressure: 2020.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Article
  9. The 2015 Canadian Hypertension Education Program (CHEP) guidelines for pharmacists: An update.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC · 2015
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Finlay A McAlisterDivision of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada. Finlay.McAlister@ualberta.ca
Cynthia Robitaille
Cathleen Gillespie
Keming Yuan
Deepa P Rao
Steven Grover
Sulan Dai
Helen Johansen
Michel Joffres
Fleetwood Loustalot
Norm Campbell

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundIt is unclear whether blood pressure control varies across the spectrum of atherosclerotic risk.

methodsWe used data from nonpregnant adults who had fasted laboratory samples drawn for the 2007-2009 cycle of the Canadian Health Measures Survey (CHMS) or the 2005-2008 US National Health and Nutrition Examination Survey (NHANES).

resultsThe 1692 CHMS subjects and 3541 NHANES participants were demographically similar (aged a mean of 45 years), although NHANES participants exhibited higher obesity rates (33.8% vs. 22.2%, P < 0.001). Over 80% of CHMS and NHANES subjects with hypertension had at least 1 other cardiovascular risk factor. As the number of atherosclerotic risk factors increased, hypertension prevalence increased, but blood pressure control rates improved (from 48% among hypertensives with no other risk factors in CHMS to 77% among those with 3 or more risk factors, and from 35% to 53% in NHANES). However, the converse was not true: The distribution of Framingham risk scores for those subjects with "controlled hypertension" was nearly identical to the distribution among those adults with uncontrolled hypertension in both CHMS and NHANES and substantially higher than scores in normotensive subjects.

conclusionsAlthough control of blood pressure was better in patients with multiple atherosclerotic risk factors, hypertensives with controlled blood pressures exhibited risk-factor profiles similar to those of participants with uncontrolled blood pressures. This suggests the need, in educational messaging and therapy decision making, for an increased focus on total atherosclerotic risk rather than just blood pressure control.

Indexed as

AdultAtherosclerosisBlood PressureCanadaCardiovascular DiseasesFemaleHealth SurveysHumansHypertensionMaleMiddle AgedNutrition SurveysObesityPrevalenceRisk FactorsUnited States

Identifiers

PMID23454038
PMCPMC4494043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.