Evidence map›Paper›PMID 23452306›Full record

ArticleBMC medical informatics and decision making2013

Improving sensitivity of machine learning methods for automated case identification from free-text electronic medical records.

Zubair Afzal, Martijn J Schuemie, Jan C van Blijderveen, Elif F Sen, Miriam C J M Sturkenboom, Jan A Kors

Abstract readComparative Study
In one paragraph

Article in BMC medical informatics and decision making, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Metabolic Syndrome Prediction Models Using Machine Learning and Sasang Constitution Type.Evidence-based complementary and alternative medicine : eCAM · 2021
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  15. Development of a Computational Model to Predict Excess Body Fat in Adolescents through Low Cost Variables.International journal of environmental research and public health · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zubair AfzalDepartment of Medical Informatics, Erasmus Medical Center, P,O, Box 2040, Rotterdam 3000CA, Netherlands. m.afzal@erasmusmc.nl
Martijn J Schuemie
Jan C van Blijderveen
Elif F Sen
Miriam C J M Sturkenboom
Jan A Kors

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDistinguishing cases from non-cases in free-text electronic medical records is an important initial step in observational epidemiological studies, but manual record validation is time-consuming and cumbersome. We compared different approaches to develop an automatic case identification system with high sensitivity to assist manual annotators.

methodsWe used four different machine-learning algorithms to build case identification systems for two data sets, one comprising hepatobiliary disease patients, the other acute renal failure patients. To improve the sensitivity of the systems, we varied the imbalance ratio between positive cases and negative cases using under- and over-sampling techniques, and applied cost-sensitive learning with various misclassification costs.

resultsFor the hepatobiliary data set, we obtained a high sensitivity of 0.95 (on a par with manual annotators, as compared to 0.91 for a baseline classifier) with specificity 0.56. For the acute renal failure data set, sensitivity increased from 0.69 to 0.89, with specificity 0.59. Performance differences between the various machine-learning algorithms were not large. Classifiers performed best when trained on data sets with imbalance ratio below 10.

conclusionsWe were able to achieve high sensitivity with moderate specificity for automatic case identification on two data sets of electronic medical records. Such a high-sensitive case identification system can be used as a pre-filter to significantly reduce the burden of manual record validation.

Indexed as

Artificial IntelligenceElectronic Health RecordsAcute Kidney InjuryAlgorithmsBiliary Tract DiseasesData CollectionHumansLiver Diseases

Identifiers

PMID23452306
PMCPMC3602667

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.