ArticleEnvironmental science & technology2013
PCBs and OH-PCBs in serum from children and mothers in urban and rural U.S. communities.
Article in Environmental science & technology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 63 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 95 citations in OpenAlex.
- Developmental exposure to a human-relevant PCB mixture: impacts on PCB congeners, metabolites, and drug-metabolizing enzymes in the bladder of post-weaning mice.Archives of toxicology · 2026Article
- The Bladder as a Target for PCB Toxicity: Evidence from PCB Levels, Phase I Metabolite Levels, and Cytochrome P450 Expression Following Developmental Exposure to a Human-Relevant PCB Mixture in Mice.Chemical research in toxicology · 2026Article
- Aroclor 1254 inhibits anti-inflammatory macrophage polarization through an AhR-dependent mechanism.Journal of the Endocrine Society · 2026Article
- Characterizing the presence of polychlorinated biphenyls within Biota Found in New Mexico.PloS one · 2026Article
- Transgenerational toxicity of Aroclor 1232 by inhalational route in mouse model.Toxicology reports · 2025Article
- Whole-Body Disposition and Metabolism of [Environmental science & technology · 2025Article
- Polychlorinated biphenyls induce immunometabolic switch of antiinflammatory macrophages toward an inflammatory phenotype.PNAS nexus · 2025Article
- Astrocyte Mitochondria Are a Sensitive Target of PCB52 and its Human-Relevant Metabolites.ACS chemical neuroscience · 2024Article
- Quantifying 209 Polychlorinated Biphenyl Congeners in Silicone Wristbands to Evaluate Differences in Exposure among Demolition Workers.Environmental science & technology · 2024Article
- Complex roles for sulfation in the toxicities of polychlorinated biphenyls.Critical reviews in toxicology · 2024Review
- Predicted versus observed activity of PCB mixtures toward the ryanodine receptor.Neurotoxicology · 2024Article
- Article
- Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples.Environmental science & technology · 2022Article
- Inadvertently Generated PCBs in Consumer Products: Concentrations, Fate and Transport, and Preliminary Exposure Assessment.Environmental science & technology · 2022Article
- Assessment of Polychlorinated Biphenyls and Their Hydroxylated Metabolites in Postmortem Human Brain Samples: Age and Brain Region Differences.Environmental science & technology · 2022Article
- PCB Sulfates in Serum from Mothers and Children in Urban and Rural U.S. Communities.Environmental science & technology · 2022Article
- Hydroxylated Polychlorinated Biphenyls Are Emerging Legacy Pollutants in Contaminated Sediments.Environmental science & technology · 2022Article
- Interconversion between methoxylated, hydroxylated and sulfated metabolites of PCB 3 in whole poplar plants.The Science of the total environment · 2021Article
- Room-to-Room Variability of Airborne Polychlorinated Biphenyls in Schools and the Application of Air Sampling for Targeted Source Evaluation.Environmental science & technology · 2021Article
- Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samples.Regulatory toxicology and pharmacology : RTP · 2021Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
East Chicago, Indiana is a heavily industrialized community bisected by the Indiana Harbor and Ship Canal, which volatilizes ~7.5 kg/yr polychlorinated biphenyls (PCBs). In contrast, the rural Columbus Junction, Iowa area has no known current or past PCB industrial sources. Blood from children and their mothers from these communities were collected April 2008 to January 2009 (n = 177). Sera were analyzed for all 209 PCBs and 4 hydroxylated PCBs (OH-PCBs). Sum PCBs ranged from nondetect to 658 ng/g lw (median = 33.5 ng/g lw). Sum OH-PCBs ranged from nondetect to 1.2 ng/g fw (median = 0.07 ng/g fw). These concentrations are similar to those reported in other populations without high dietary PCB intake. Differences between the two communities were subtle. PCBs were detected in more East Chicago mothers and children than Columbus Junction mothers and children, and children from East Chicago were enriched in lower-molecular weight PCBs. East Chicago and Columbus Junction residents had similar levels of total and individual PCBs and OH-PCBs in their blood. Concentrations of parent PCBs correlated with concentrations of OH-PCBs. This is the first temporally and methodologically consistent study to evaluate all 209 PCBs and major metabolites in two generations of people living in urban and rural areas of the United States.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.