Evidence map›Paper›PMID 23452034›Full record

ArticleJournal of the American Geriatrics Society2013

Geriatric syndromes and incident disability in older women: results from the women's health initiative observational study.

Andrea L Rosso, Charles B Eaton, Robert Wallace, Rachel Gold, Marcia L Stefanick, Judith K Ockene, J David Curb, Yvonne L Michael

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.

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  11. Geriatric syndromes in women living with HIV.Current opinion in HIV and AIDS · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 1 country.

Andrea L RossoDepartment of Epidemiology, Center for Aging and Population Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Charles B Eaton
Robert Wallace
Rachel Gold
Marcia L Stefanick
Judith K Ockene
J David Curb
Yvonne L Michael
Brown University · USDrexel University · USKaiser Permanente Center for Health Research · USStanford University · USUniversity of Hawaiʻi at Mānoa · USUniversity of Iowa · USUniversity of Massachusetts Chan Medical School · USUniversity of Pittsburgh · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Hormone therapy and change in functional status in Women's Health InitiativeR03AG031973 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI MICHAEL, YVONNE LOUISE · 2009 to 2010
$137k
NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100003INHLBI NIH HHS HHSN268201100004INHLBI NIH HHS HHSN268201100046CNIA NIH HHS HHSN271201100004CNIA NIH HHS P30 AG024827NIA NIH HHS R03 AG031973NIA NIH HHS R03AG031973WHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004C
6 · The paper itself

Abstract

objectivesTo determine how the number of geriatric syndromes is associated with incident disability in community-based populations of older adults.

designLongitudinal analysis from the Women's Health Initiative Observational Study (WHI-OS).

settingCommunity.

participantsTwenty-nine thousand five hundred forty-four women aged 65 and older enrolled in the WHI-OS and free of disability in activities of daily living (ADLs) at baseline. MEASUREMENTS: Geriatric syndromes (high depressive symptoms, dizziness, falls, hearing or visual impairment, osteoporosis, polypharmacy, syncope, sleep disturbance, and urinary incontinence) were self-reported at baseline and 3-year follow-up. Disability was defined as dependence in any ADL and was assessed at baseline and follow-up. Chronic diseases were measured according to a modified Charlson Index.

resultsGeriatric syndromes were common in this population of women; 76.3% had at least one syndrome at baseline. Greater number of geriatric syndromes at baseline was significantly associated with greater risk of incident ADL disability at follow-up (P ≤ .001). Adjusted risk ratios were 1.21 (95% confidence interval (CI) = 0.78-1.87) for a single syndrome and 6.64 (95% CI = 4.15-10.62) for five or more syndromes compared with no syndromes. These results were only slightly attenuated after adjustment for number of chronic diseases or pain.

conclusionGeriatric syndromes are significantly associated with onset of disability in older women; this association is not simply a result of chronic disease or pain. A better understanding of how these conditions contribute to disablement is needed. Geriatric syndrome assessment should be considered along with chronic disease management in the prevention of disability in older women.

Indexed as

Activities of Daily LivingGeriatric AssessmentHealth StatusWomen's HealthAgedChronic DiseaseFemaleFollow-Up StudiesGeriatricsHumansIncidencePersons with DisabilitiesRiskSyndromeUnited States

Identifiers

PMID23452034
PMCPMC3602348
OpenAlexW2011122274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.