Evidence map›Paper›PMID 23451892›Full record

ReviewAnnual review of biophysics2013

Advances, interactions, and future developments in the CNS, Phenix, and Rosetta structural biology software systems.

Paul D Adams, David Baker, Axel T Brunger, Rhiju Das, Frank DiMaio, Randy J Read, David C Richardson, Jane S Richardson, Thomas C Terwilliger

Abstract readReview
In one paragraph

Review in Annual review of biophysics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Getting to the bottom of lncRNA mechanism: structure-function relationships.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
  13. Article
  14. Article
  15. Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. An inhibitor of complement C5 provides structural insights into activation.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paul D AdamsLawrence Berkeley National Laboratory, Berkeley, California 94720, USA. PDAdams@lbl.gov
David Baker
Axel T Brunger
Rhiju Das
Frank DiMaio
Randy J Read
David C Richardson
Jane S Richardson
Thomas C Terwilliger

Funding

PROJECT 5 - DUKE - STRUCTURE VALIDATION AND IMPROVEMENT FOR PROTEINS AND N. ACIDSP01GM063210 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI ADAMS, PAUL DAVID · 2001 to 2021
$33.5M
High resolution structure modeling with RosettaR01GM092802 · NIGMS · UNIVERSITY OF WASHINGTON · PI BAKER, DAVID · 2010 to 2017
$2.3M
Syk in Mitochondrial Stress Signaling and Insulin ResistanceK08GM102718 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI PATTERSON, HEIDE CHRISTINE · 2012 to 2015
$800k
Correcting Pervasive Errors in RNA Crystallography with RosettaR21GM102716 · NIGMS · STANFORD UNIVERSITY · PI DAS, RHIJU · 2012 to 2013
$302k
NIGMS NIH HHS GM063210NIGMS NIH HHS GM092802-03NIGMS NIH HHS K08 GM102718NIGMS NIH HHS P01 GM063210NIGMS NIH HHS R01 GM092802NIGMS NIH HHS R21 GM102716NIGMS NIH HHS R21 GM102718-01Wellcome Trust 082961
6 · The paper itself

Abstract

Advances in our understanding of macromolecular structure come from experimental methods, such as X-ray crystallography, and also computational analysis of the growing number of atomic models obtained from such experiments. The later analyses have made it possible to develop powerful tools for structure prediction and optimization in the absence of experimental data. In recent years, a synergy between these computational methods for crystallographic structure determination and structure prediction and optimization has begun to be exploited. We review some of the advances in the algorithms used for crystallographic structure determination in the Phenix and Crystallography & NMR System software packages and describe how methods from ab initio structure prediction and refinement in Rosetta have been applied to challenging crystallographic problems. The prospects for future improvement of these methods are discussed.

Indexed as

Crystallography, X-RayModels, MolecularSoftwareAlgorithmsAnimalsHumansMagnetic Resonance SpectroscopyMolecular ConformationProteinsRNAProteinsRNA

Identifiers

PMID23451892
PMCPMC8262117

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.