Evidence map›Paper›PMID 23450784›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2013

Silica-based branched hollow microfibers as a biomimetic extracellular matrix for promoting tumor cell growth in vitro and in vivo.

Penghe Qiu, Xuewei Qu, Daniel J Brackett, Megan R Lerner, Dong Li, Chuanbin Mao

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Penghe QiuDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019, USA.
Xuewei Qu
Daniel J Brackett
Megan R Lerner
Dong Li
Chuanbin Mao

Funding

Phage-inspired nanoparticles with genetically tunable target-specificityR01HL092526 · NHLBI · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2009 to 2010
$806k
Phage-Mimetic Nanorods for Targeted Breast Cancer TreatmentR21EB009909 · NIBIB · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2009 to 2010
$399k
Tubulin-Binding Upconversion Nanoparticles for Breast-Cancer Imaging and TherapyR21EB015190 · NIBIB · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2012 to 2013
$398k
Bone-seeking and cell-targeting non-viral vectors for BMP-2 gene deliveryR03AR056848 · NIAMS · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2009 to 2011
$222k
NHLBI NIH HHS 5R01HL092526-02NHLBI NIH HHS R01 HL092526NIAMS NIH HHS 4R03AR056848-03NIAMS NIH HHS R03 AR056848NIBIB NIH HHS 1R21EB015190-01A1NIBIB NIH HHS 5R21EB009909-02NIBIB NIH HHS R21 EB009909NIBIB NIH HHS R21 EB015190
6 · The paper itself

Abstract

A novel scaffold composed of loosely branched hollow silica microfibers that has been proven to be highly biocompatible is proposed for the 3D culture of cancer cells. The MCF-7 cancer cells can grow and proliferate freely inside the scaffold in the form of multicellular spheroids. MCF-7 cancer cells cultured on the current 3D silica scaffold retained significantly more oncological characters than those cultured on the conventional 2D substrate and can serve as in vitro tumor model for studying cancer treatment.

Indexed as

Tissue ScaffoldsAnimalsBiomimetic MaterialsCell ProliferationEquipment DesignEquipment Failure AnalysisExtracellular MatrixHumansMaterials TestingMCF-7 CellsMiceMice, NudeNeoplasms, ExperimentalSilicon DioxideSurface PropertiesTissue EngineeringSilicon Dioxide

Identifiers

PMID23450784
PMCPMC3731149

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.