Evidence map›Paper›PMID 23449968›Full record

ArticleCurrent neuropharmacology2012

The developing utility of zebrafish models for cognitive enhancers research.

Adam Michael Stewart, Allan V Kalueff

Open access · bronzeAbstract read
In one paragraph

Article in Current neuropharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 56 citations in OpenAlex.

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  16. Frontiers in pharmacology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Adam Michael StewartBrain-Body Center, Department of Psychiatry, University of Illinois at Chicago, 1601 W. Taylor Ave., Chicago, IL 60612, USA.
Allan V Kalueff
Tulane University · USUniversity of Illinois Chicago · US

Funding

Developing adult zebrafish-based models to study hallucinogenic drug actionR03DA030900 · NIDA · TULANE UNIVERSITY OF LOUISIANA · PI KALUEFF, ALLAN V · 2010 to 2012
$87k
NIDA NIH HHS R03 DA030900
6 · The paper itself

Abstract

Whereas cognitive impairment is a common symptom in multiple brain disorders, predictive and high-throughput animal models of cognition and behavior are becoming increasingly important in the field of translational neuroscience research. In particular, reliable models of the cognitive deficits characteristic of numerous neurobehavioral disorders such as Alzheimer's disease and schizophrenia have become a significant focus of investigation. While rodents have traditionally been used to study cognitive phenotypes, zebrafish (Danio rerio) are gaining popularity as an excellent model to complement current translational neuroscience research. Here we discuss recent advances in pharmacological and genetic approaches using zebrafish models to study cognitive impairments and to discover novel cognitive enhancers and neuroprotective mechanisms.

Indexed as

Cognitioncognitive enhancersdrug screeningneurobehavioral disordersneuroprotective agentszebrafish.

Identifiers

PMID23449968
PMCPMC3468880
OpenAlexW2066853410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.