ArticleStudies in mycology2013
Germination of conidia of Aspergillus niger is accompanied by major changes in RNA profiles.
Article in Studies in mycology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed.
- Insights intomSphere · 2026Article
- Conserved storage-carbohydrate metabolic modules are rewired during germination ofFrontiers in fungal biology · 2026Article
- Comparative transcriptomics reveal contrasting strategies between a fungal plant pathogen and an endophyte during initial host colonization.Microbiology spectrum · 2025Article
- Different starch sources and amino acid levels on growth performance, starch and amino acids digestion, absorption and metabolism of 0- to 3-week-old broilers fed low protein diet.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Study on the metabolic changes and regulatory mechanism ofMicrobiology spectrum · 2024Article
- Biogenesis, germination, and pathogenesis ofMicrobiology and molecular biology reviews : MMBR · 2024Review
- Compatible solutes determine the heat resistance of conidia.Fungal biology and biotechnology · 2023Article
- Global Transcriptomic Changes Elicited byJournal of fungi (Basel, Switzerland) · 2023Article
- The breaking of fungal spore dormancy: A coordinated transition.PLoS biology · 2023Article
- Solid-state NMR molecular snapshots ofProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Genome-Wide Gene Expression Analyses of the AtfA/AtfB-Mediated Menadione Stress Response inCells · 2023Article
- Identification of lncRNA and weighted gene coexpression network analysis of germinatingMycology · 2023Article
- LaeA regulates morphological development and ochratoxin A biosynthesis in Aspergillus niger.Mycotoxin research · 2022Article
- Effect of Shock Waves on the Growth ofJournal of fungi (Basel, Switzerland) · 2022Article
- Effect of Water Activity on Conidia Germination inMicroorganisms · 2022Article
- Article
- Differential Expression of Cell Wall Remodeling Genes Is Part of the Dynamic Phase-Specific Transcriptional Program of Conidial Germination ofJournal of fungi (Basel, Switzerland) · 2022Article
- Novel Treatment Approach for Aspergilloses by Targeting Germination.Journal of fungi (Basel, Switzerland) · 2022Review
- A Special Phenotype of AconidialJournal of fungi (Basel, Switzerland) · 2022Article
- A highly efficient stratagem for protoplast isolation and genetic transformation in filamentous fungus Colletotrichum falcatum.Folia microbiologica · 2022Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The transcriptome of conidia of Aspergillus niger was analysed during the first 8 h of germination. Dormant conidia started to grow isotropically two h after inoculation in liquid medium. Isotropic growth changed to polarised growth after 6 h, which coincided with one round of mitosis. Dormant conidia contained transcripts from 4 626 genes. The number of genes with transcripts decreased to 3 557 after 2 h of germination, after which an increase was observed with 4 780 expressed genes 8 h after inoculation. The RNA composition of dormant conidia was substantially different than all the subsequent stages of germination. The correlation coefficient between the RNA profiles of 0 h and 8 h was 0.46. They were between 0.76-0.93 when profiles of 2, 4 and 6 h were compared with that of 8 h. Dormant conidia were characterised by high levels of transcripts of genes involved in the formation of protecting components such as trehalose, mannitol, protective proteins (e.g. heat shock proteins and catalase). Transcripts belonging to the Functional Gene Categories (FunCat) protein synthesis, cell cycle and DNA processing and respiration were over-represented in the up-regulated genes at 2 h, whereas metabolism and cell cycle and DNA processing were over-represented in the up-regulated genes at 4 h. At 6 h and 8 h no functional gene classes were over- or under-represented in the differentially expressed genes. Taken together, it is concluded that the transcriptome of conidia changes dramatically during the first two h and that initiation of protein synthesis and respiration are important during early stages of germination.
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