ArticleDevelopmental cell2013
Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
Article in Developmental cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
130 citing papers in PubMed, 269 citations in OpenAlex.
- The miR319-LsTCP4 module regulates de novo shoot regeneration in lettuce.Plant cell reports · 2026Article
- LMI1 and TCP4 homologs form a functional module to regulate lateral petal asymmetric bending in Delphinium anthriscifolium.The Plant journal : for cell and molecular biology · 2026Article
- Integrated analysis of ATAC-seq and RNA-seq reveals the TCP-ARF molecular module related to pathogenic process of phytoplasma infection in Paulownia fortunei.BMC genomics · 2026Article
- BRAHMA represses STOP1-NRT1.1 module to control plant rhizosphere alkalization and acid stress adaptation.Nature communications · 2026Article
- Cytokinin availability and chloroplast functional lifetime in senescing leaves.Frontiers in plant science · 2026Review
- Big data approaches to understanding gene regulatory networks in the shoot apical meristem andFrontiers in plant science · 2026Review
- Article
- TCP3-mediated regulation of cell expansion in Arabidopsis thaliana.The New phytologist · 2025Article
- HC-Pro Disrupts miR319-TCP Regulatory Pathways to Induce Sterility in Transgenic Plants.International journal of molecular sciences · 2025Article
- Transcriptomic analysis of wrinkled leaf development of Tai-cai (Brassica rapa var. tai-tsai) and its synthetic allotetraploid via RNA and miRNA sequencing.Plant molecular biology · 2025Article
- Review
- SWI/SNF-type complexes-transcription factor interplay: a key regulatory interaction.Cellular & molecular biology letters · 2025Review
- Building beauty: Understanding how hormone signaling regulates petal patterning and morphogenesis.The Plant journal : for cell and molecular biology · 2025Review
- Unraveling TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR Transcription Factors in Safflower: A Blueprint for Stress Resilience and Metabolic Regulation.Molecules (Basel, Switzerland) · 2025Article
- Characterization of DNA methylation reader proteins inGenome research · 2024Article
- Multi Characteristic Analysis of Vascular Cambium Cells inPlants (Basel, Switzerland) · 2024Article
- Primary multistep phosphorelay activation comprises both cytokinin and abiotic stress responses: insights from comparative analysis of Brassica type-A response regulators.Journal of experimental botany · 2024Article
- Epigenetics and plant hormone dynamics: a functional and methodological perspective.Journal of experimental botany · 2024Review
- Strigolactone induces D14-dependent large-scale changes in gene expression requiring SWI/SNF chromatin remodellers.The Plant journal : for cell and molecular biology · 2024Article
- Chromatin sensing: integration of environmental signals to reprogram plant development through chromatin regulators.Journal of experimental botany · 2024Review
70 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
Abstract
Plant shoots display indeterminate growth, while their evolutionary decedents, the leaves, are determinate. Determinate leaf growth is conditioned by the CIN-TCP transcription factors, which promote leaf maturation and are negatively regulated by miR319 in leaf primordia. Here we show that CIN-TCPs reduce leaf sensitivity to cytokinin (CK), a phytohormone implicated in inhibition of differentiation in the shoot. We identify the SWI/SNF chromatin remodeling ATPase BRAHMA (BRM) as a genetic mediator of CIN-TCP activities and CK responses. An interactome screen further revealed that SWI/SNF complex components including BRM preferentially interacted with basic-helix-loop-helix (bHLH) transcription factors and the bHLH-related CIN-TCPs. Indeed, TCP4 and BRM interacted in planta. Both TCP4 and BRM bound the promoter of an inhibitor of CK responses, ARR16, and induced its expression. Reconstituting ARR16 levels in leaves with reduced CIN-TCP activity restored normal growth. Thus, CIN-TCP and BRM together promote determinate leaf growth by stage-specific modification of CK responses.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.