ArticleDevelopmental cell2013
Three-dimensional epithelial morphogenesis in the developing Drosophila egg.
Article in Developmental cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 147 citations in OpenAlex.
- Supracellular actomyosin assemblies: master coordinators of development.Development (Cambridge, England) · 2025Review
- Growth regulation bringing modularity to morphogenesis of complex three-dimensional exoskeletons.Proceedings. Biological sciences · 2024Article
- Deep learning reveals a damage signalling hierarchy that coordinates different cell behaviours driving wound re-epithelialisation.Development (Cambridge, England) · 2024Article
- Active shape programming drivesScience advances · 2024Article
- Balancing competing effects of tissue growth and cytoskeletal regulation during Drosophila wing disc development.Nature communications · 2024Article
- Finishing the egg.Genetics · 2024Article
- Engineering tools for quantifying and manipulating forces in epithelia.Biophysics reviews · 2023Review
- Two phases for centripetal migration of Drosophila melanogaster follicle cells: initial ingression followed by epithelial migration.Development (Cambridge, England) · 2023Article
- Imaginal disk growth factors are Drosophila chitinase-like proteins with roles in morphogenesis and CO2 response.Genetics · 2023Article
- Live Imaging of Nurse Cell Behavior in Late Stages of Drosophila Oogenesis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Modelling the Collective Mechanical Regulation of the Structure and Morphology of Epithelial Cell Layers.Frontiers in cell and developmental biology · 2022Article
- Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis.Cell · 2021Article
- Forced into shape: Mechanical forces in Drosophila development and homeostasis.Seminars in cell & developmental biology · 2021Review
- A mesoscale mechanical model of cellular interactions.Biophysical journal · 2021Article
- Patient-Specific Organoid and Organ-on-a-Chip: 3D Cell-Culture Meets 3D Printing and Numerical Simulation.Advanced biology · 2021Review
- Bridging from single to collective cell migration: A review of models and links to experiments.PLoS computational biology · 2020Review
- Detecting New Allies: Modifier Screen Identifies a Genetic Interaction BetweenG3 (Bethesda, Md.) · 2020Article
- Viscoelastic voyages - Biophysical perspectives on cell intercalation during Drosophila gastrulation.Seminars in cell & developmental biology · 2020Review
- Model to Link Cell Shape and Polarity with Organogenesis.iScience · 2020Article
- Polarized cellular mechano-response system for maintaining radial size in developing epithelial tubes.Development (Cambridge, England) · 2019Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Morphogenesis of the respiratory appendages on eggshells of Drosophila species provides a powerful experimental system for studying how cell sheets give rise to complex three-dimensional structures. In Drosophila melanogaster, each of the two tubular eggshell appendages is derived from a primordium comprising two distinct cell types. Using live imaging and three-dimensional image reconstruction, we demonstrate that the transformation of this two-dimensional primordium into a tube involves out-of-plane bending followed by a sequence of spatially ordered cell intercalations. These morphological transformations correlate with the appearance of complementary distributions of myosin and Bazooka in the primordium. These distributions suggest that a two-dimensional pattern of line tensions along cell-cell edges on the apical side of the epithelium is sufficient to produce the observed changes in morphology. Computational modeling shows that this mechanism could explain the main features of tissue deformation and cell rearrangements observed during three-dimensional morphogenesis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.