Evidence map›Paper›PMID 23449394›Full record

ReviewCell death and differentiation2013

Shaping organisms with apoptosis.

M Suzanne, H Steller

Open access · hybridAbstract readReview
In one paragraph

Review in Cell death and differentiation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 236 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Inferring Cell Differentiation Dynamics with Unobserved Progenitors.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Review
  9. Engineering Efferocytosis for Bone Regeneration.Macromolecular bioscience · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Mesenchymal stem cell conditioned medium improves hypoxic injury to protect islet graft function.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Macrophage variants in laboratory research: most are well done, but some are RAW.Frontiers in cellular and infection microbiology · 2024
    Review

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

M SuzanneUniversité de Toulouse, UPS, LBCMCP; F-31062 Toulouse, France.
H Steller
Howard Hughes Medical Institute · USUniversité Toulouse III - Paul Sabatier · FR

Funding

Proteasome Regulation and Function in Cellular RemodelingR01GM060124 · NIGMS · ROCKEFELLER UNIVERSITY · PI STELLER, HERMANN · 1999 to 2018
$5.4M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM060124NIGMS NIH HHS R01GM60124
6 · The paper itself

Abstract

Programmed cell death is an important process during development that serves to remove superfluous cells and tissues, such as larval organs during metamorphosis, supernumerary cells during nervous system development, muscle patterning and cardiac morphogenesis. Different kinds of cell death have been observed and were originally classified based on distinct morphological features: (1) type I programmed cell death (PCD) or apoptosis is recognized by cell rounding, DNA fragmentation, externalization of phosphatidyl serine, caspase activation and the absence of inflammatory reaction, (2) type II PCD or autophagy is characterized by the presence of large vacuoles and the fact that cells can recover until very late in the process and (3) necrosis is associated with an uncontrolled release of the intracellular content after cell swelling and rupture of the membrane, which commonly induces an inflammatory response. In this review, we will focus exclusively on developmental cell death by apoptosis and its role in tissue remodeling.

Indexed as

AnimalsApoptosisAutophagyCell MovementDrosophilaHumansMiceMorphogenesisNecrosisSignal Transduction

Identifiers

PMID23449394
PMCPMC3619238
OpenAlexW1976780320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.