Evidence map›Paper›PMID 23448938›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2013

Effects of low-dose dopamine on urine output in normotensive very low birth weight neonates.

J L Crouchley, P B Smith, C M Cotten, C D Hornik, R N Goldberg, J W Foreman, J L Wynn

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Physiology-guided vasoactive therapy in neonates: rethinking dopamine as first-line.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  2. Use of vasopressors for septic shock in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  3. Article
  4. Management of Shock in Neonates.Indian journal of pediatrics · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

J L CrouchleyDepartment of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.
P B Smith
C M Cotten
C D Hornik
R N Goldberg
J W Foreman
J L Wynn
Duke Medical Center · USDuke University · US

Funding

PHARMACOKINETICS OF ANTIMICROBIAL AGENTS IN HIGH RISK INFANTSK23HD060040 · NICHD · DUKE UNIVERSITY · PI SMITH, PHILLIP BRIAN · 2009 to 2012
$445k
NICHD NIH HHS K23 HD060040
6 · The paper itself

Abstract

objectiveTo determine the effects of low-dose dopamine on urine output (UOP) in very low birth weight premature neonates. STUDY

designRetrospective cohort study of all low-dose (3-5 μg kg(-1) per min) dopamine infusions >24-h duration in neonates 1500 g and 32 weeks gestation from August 2009 through September 2011. Linear regression was used to estimate the impact of covariates on UOP.

resultWe identified 91 episodes of low-dose dopamine use in 65 neonates. Increased UOP occurred in 64% of episodes. Low-dose dopamine use was associated with a 0.6 ml kg(-1) h(-1) increase in UOP (P<0.001) and a 1.3 ml kg(-1)h(-1) increase when baseline UOP was <1.5 ml kg(-1) h(-1) (P<0.001). The improvement remained statistically significant after controlling for medications (diuretics and hydrocortisone) and fluid intake.

conclusionLow-dose dopamine use was associated with increased UOP in very low birth weight neonates.

Indexed as

DopamineFemaleHumansInfant, NewbornInfant, Very Low Birth WeightKidneyMaleRetrospective StudiesUrinationUrineDopamine

Identifiers

PMID23448938
PMCPMC4028044
OpenAlexW2048787870

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.