ArticleBMC nephrology2013
Reference values for glomerular filtration rate in healthy Brazilian adults.
Article in BMC nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Gender-specific spKt/V thresholds associated with mortality in maintenance hemodialysis patients: a nationwide Korean cohort study.Scientific reports · 2026Article
- Applicability of 14 Formulas for Estimating Glomerular Filtration Rate in the Evaluation of Renal Function before and after Nephron-Sparing Surgery in Patients with Renal Tumors.Contrast media & molecular imaging · 2022Article
- Early neurovascular retinal changes detected by swept-source OCT in type 2 diabetes and association with diabetic kidney disease.International journal of retina and vitreous · 2021Article
- Reference values of glomerular filtration rate for healthy adults in southern China: a cross-sectional survey.Therapeutic advances in chronic disease · 2021Article
- CKD: A Call for an Age-Adapted Definition.Journal of the American Society of Nephrology : JASN · 2019Review
- The effects of obesity on kidney function: a challenge for nephrologists.Jornal brasileiro de nefrologia · 2019Article
- Age-dependent reference intervals for estimated and measured glomerular filtration rate.Clinical kidney journal · 2017Article
- Normalization of glomerular filtration rate in obese children.Pediatric nephrology (Berlin, Germany) · 2016Article
- Tumor-Specific D-Dimer Concentration Ranges and Influencing Factors: A Cross-Sectional Study.PloS one · 2016Article
- Association between estimated glomerular filtration rate and sodium excretion in urine of African descendants in Brazil: a population-based study.Jornal brasileiro de nefrologiaArticle
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Authors and funding
6 authors.
Funding
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Abstract
backgroundGlomerular filtration rate (GFR) is the best index of renal function, but age, gender and ethnicity can putatively affect its values. The aim of this study was to establish reference values for GFR in healthy Brazilian subjects while taking these factors into account.
methodsIn this cross-sectional study, GFR was measured by the 51Cr-EDTA single-injection method. GFR reference values were developed according to CLSI Guidelines for Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory (CLSI C28 protocol).
resultsThe age range of the 285 healthy individuals was 19 to 70 years, 57% were females, and GFR was 106 ± 18 mL/min/1.73 m(2). There was no difference between male and female GFRs (108 ± 18 vs. 104 ± 18 mL/min/1.73 m(2) respectively, P = 0.134), and reference values were therefore developed from the pooled sample. GFR values were lower in subjects aged ≥45 years as compared with those younger than 45 years (98 ± 15 vs.112 ± 18 mL/min/1.73 m(2), P < 0.001). Based on mean ± 2 SD, GFR reference values were 76 to 148 mL/min/1.73 m(2) for subjects younger than 45 years and 68 to 128 mL/min/1.73 m(2) for individuals older than 45 years, irrespective of gender.
conclusionThe age-adjusted reference intervals reported may be reliably adopted to evaluate kidney function, since they are based on recommended standards.
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