ReviewACS chemical neuroscience2013
Physiological fluctuations in brain temperature as a factor affecting electrochemical evaluations of extracellular glutamate and glucose in behavioral experiments.
Review in ACS chemical neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 41 citations in OpenAlex.
- A low-cost perfusion heating system for slice electrophysiology.Scientific reports · 2024Article
- Nonenzymatic Electrochemical Glutamate Sensor Using Copper Oxide Nanomaterials and Multiwall Carbon Nanotubes.Biosensors · 2023Article
- Contrasting dose-dependent effects of acute intravenous methamphetamine on lateral hypothalamic extracellular glucose dynamics in male and female rats.Journal of neurophysiology · 2022Article
- Voluntary Behavior and Training Conditions ModulateFrontiers in neuroscience · 2021Article
- Infrared neural stimulation and inhibition using an implantable silicon photonic microdevice.Microsystems & nanoengineering · 2020Article
- Interactions of benzodiazepines with heroin: Respiratory depression, temperature effects, and behavior.Neuropharmacology · 2019Article
- Brain temperature and its role in physiology and pathophysiology: Lessons from 20 years of thermorecording.Temperature (Austin, Tex.) · 2019Review
- Closed-Loop Implantable Therapeutic Neuromodulation Systems Based on Neurochemical Monitoring.Frontiers in neuroscience · 2019Review
- Changes in brain oxygen and glucose induced by oxycodone: Relationships with brain temperature and peripheral vascular tone.Neuropharmacology · 2018Article
- Brain Hyperglycemia Induced by Heroin: Association with Metabolic Neural Activation.ACS chemical neuroscience · 2017Article
- Effects of Systemic Metabolic Fuels on Glucose and Lactate Levels in the Brain Extracellular Compartment of the Mouse.Frontiers in neuroscience · 2017Article
- Experience-dependent escalation of glucose drinking and the development of glucose preference over fructose - association with glucose entry into the brain.The European journal of neuroscience · 2016Article
- A User-Configurable Headstage for Multimodality Neuromonitoring in Freely Moving Rats.Frontiers in neuroscience · 2016Article
- Robust Brain Hyperglycemia during General Anesthesia: Relationships with Metabolic Brain Inhibition and Vasodilation.Frontiers in physiology · 2016Article
- A review of flux considerations for in vivo neurochemical measurements.The Analyst · 2015Review
- Fluctuations in nucleus accumbens extracellular glutamate and glucose during motivated glucose-drinking behavior: dissecting the neurochemistry of reward.Journal of neurochemistry · 2015Article
- Parsing glucose entry into the brain: novel findings obtained with enzyme-based glucose biosensors.ACS chemical neuroscience · 2015Review
- Electrochemical Analysis of Neurotransmitters.Annual review of analytical chemistry (Palo Alto, Calif.) · 2015Review
- Central and peripheral contributions to dynamic changes in nucleus accumbens glucose induced by intravenous cocaine.Frontiers in neuroscience · 2015Article
- Methylenedioxypyrovalerone (MDPV) mimics cocaine in its physiological and behavioral effects but induces distinct changes in NAc glucose.Frontiers in neuroscience · 2015Article
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3 authors at 1 institution in 1 country.
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Abstract
The rate of any chemical reaction or process occurring in the brain depends on temperature. While it is commonly believed that brain temperature is a stable, tightly regulated homeostatic parameter, it fluctuates within 1-4 °C following exposure to salient arousing stimuli and neuroactive drugs, and during different behaviors. These temperature fluctuations should affect neural activity and neural functions, but the extent of this influence on neurochemical measurements in brain tissue of freely moving animals remains unclear. In this Review, we present the results of amperometric evaluations of extracellular glutamate and glucose in awake, behaving rats and discuss how naturally occurring fluctuations in brain temperature affect these measurements. While this temperature contribution appears to be insignificant for glucose because its extracellular concentrations are large, it is a serious factor for electrochemical evaluations of glutamate, which is present in brain tissue at much lower levels, showing smaller phasic fluctuations. We further discuss experimental strategies for controlling the nonspecific chemical and physical contributions to electrochemical currents detected by enzyme-based biosensors to provide greater selectivity and reliability of neurochemical measurements in behaving animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.