ArticleSmall (Weinheim an der Bergstrasse, Germany)2013
Biodegradation of single-walled carbon nanotubes by eosinophil peroxidase.
Article in Small (Weinheim an der Bergstrasse, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 195 citations in OpenAlex.
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- Biodegradation of Heterogeneous Industrial Multi-Walled Carbon Nanotubes by Pro-Inflammatory Macrophages.Nanomaterials (Basel, Switzerland) · 2024Article
- Environmental and Health Impacts of Graphene and Other Two-Dimensional Materials: A Graphene Flagship Perspective.ACS nano · 2024Review
- An Overview of the Potential of Food-Based Carbon Dots for Biomedical Applications.International journal of molecular sciences · 2023Review
- Application of Nanomaterials in the Production of Biomolecules in Microalgae: A Review.Marine drugs · 2023Review
- A new capacity of gut microbiota: Fermentation of engineered inorganic carbon nanomaterials into endogenous organic metabolites.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Gobind's last graduate student.Biophysical reviews · 2023Article
- Long-term continuous degradation of carbon nanotubes by a bacteria-driven Fenton reaction.Frontiers in microbiology · 2023Article
- Colloidal Behavior and Biodegradation of Engineered Carbon-Based Nanomaterials in Aquatic Environment.Nanomaterials (Basel, Switzerland) · 2022Review
- Nitrogen-Doped Carbon Nanotube Cups for Cancer Therapy.ACS applied nano materials · 2022Article
- Immunotoxicity of Carbon-Based Nanomaterials, Starring Phagocytes.International journal of molecular sciences · 2022Review
- Enzymatic and Cellular Degradation of Carbon-Based Biconcave Nanodisks.Micromachines · 2022Article
- Characteristics of Graphene Oxide for Gene Transfection and Controlled Release in Breast Cancer Cells.International journal of molecular sciences · 2022Review
- Redox Pioneer: Professor Valerian Kagan.Antioxidants & redox signaling · 2022Article
- Graphene Oxide and Biomolecules for the Production of Functional 3D Graphene-Based Materials.Frontiers in molecular biosciences · 2022Review
- Zebrafish Models for the Safety and Therapeutic Testing of Nanoparticles with a Focus on Macrophages.Nanomaterials (Basel, Switzerland) · 2021Review
- Ligninolytic activity of thePeerJ · 2021Article
- The Fate of SWCNTs in Mouse Peritoneal Macrophages: Exocytosis, Biodegradation, and Sustainable Retention.Frontiers in bioengineering and biotechnology · 2020Article
- The toxic influence and biodegradation of carbon nanofibers in freshwater invertebrates of the families Gammaridae, Ephemerellidae, and Chironomidae.Toxicology reports · 2020Article
- Nano-bio interactions: a neutrophil-centric view.Cell death & disease · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 5 institutions in 2 countries.
Funding
Abstract
Eosinophil peroxidase (EPO) is one of the major oxidant-producing enzymes during inflammatory states in the human lung. The degradation of single-walled carbon nanotubes (SWCNTs) upon incubation with human EPO and H₂O₂ is reported. Biodegradation of SWCNTs is higher in the presence of NaBr, but neither EPO alone nor H₂O₂ alone caused the degradation of nanotubes. Molecular modeling reveals two binding sites for SWCNTs on EPO, one located at the proximal side (same side as the catalytic site) and the other on the distal side of EPO. The oxidized groups on SWCNTs in both cases are stabilized by electrostatic interactions with positively charged residues. Biodegradation of SWCNTs can also be executed in an ex vivo culture system using primary murine eosinophils stimulated to undergo degranulation. Biodegradation is proven by a range of methods including transmission electron microscopy, UV-visible-NIR spectroscopy, Raman spectroscopy, and confocal Raman imaging. Thus, human EPO (in vitro) and ex vivo activated eosinophils mediate biodegradation of SWCNTs: an observation that is relevant to pulmonary responses to these materials.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.