Evidence map›Paper›PMID 23447060›Full record

ArticleAmerican journal of primatology2013

Development of metabolic function biomarkers in the common marmoset, Callithrix jacchus.

Toni E Ziegler, Ricki J Colman, Suzette D Tardif, Megan E Sosa, Fredrick H Wegner, Daniel J Wittwer, Hemanta Shrestha

Open access · greenAbstract read
In one paragraph

Article in American journal of primatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Development and validation of an LC-MS/MS based quantitative assay for marmoset insulin in serum.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2022
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Using snacks high in fat and protein to improve glucoregulatory function in adolescent male marmosets (Callithrix jacchus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2013
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Toni E ZieglerWisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA. ziegler@primate.wisc.edu
Ricki J Colman
Suzette D Tardif
Megan E Sosa
Fredrick H Wegner
Daniel J Wittwer
Hemanta Shrestha
University of Wisconsin–Madison · USThe University of Texas Health Science Center at San Antonio · US

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
ZOLEDRONATE PREVENTS BONE LOSS IN OVARIECTOMIZED RHESUS MONKEYSP51RR000167 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI WATKINS, DAVID I · 1985 to 2011
$106.7M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
NCATS NIH HHS 9U54TR000021NCATS NIH HHS UL1 TR000427NCRR NIH HHS 1UL1RR025011NCRR NIH HHS P51 RR000167NCRR NIH HHS RR000167NCRR NIH HHS UL1 RR025011NIH HHS P51 OD011106NIH HHS P51 OD011133
6 · The paper itself

Abstract

Metabolic assessment of a non-human primate model of metabolic syndrome and obesity requires the necessary biomarkers specific to the species. While the rhesus monkey has a number of specific assays for assessing metabolic syndrome, the marmoset does not. Furthermore, the common marmoset (Callithrix jacchus) has a small blood volume that necessitates using a single blood volume for multiple analyses. The common marmoset holds a great potential as an alternative primate model for the study of human disease but assay methods need to be developed and validated for the biomarkers of metabolic syndrome. Here we report on the adaptation, development, and validation of commercially available immunoassays for common marmoset samples in small volumes. We have performed biological validations for insulin, adiponectin, leptin, and ghrelin to demonstrate the use of these biomarkers in examining metabolic syndrome and other related diseases in the common marmoset.

Indexed as

AdiponectinAnimalsBiomarkersCallithrixEnergy MetabolismFemaleGhrelinImmunoassayInsulinLeptinMaleReproducibility of ResultsSex FactorsAdiponectinBiomarkersGhrelinInsulinLeptin

Identifiers

PMID23447060
PMCPMC3771328
OpenAlexW1508855138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.