ArticleScientific reports2013
Simultaneous measurement of deep tissue blood flow and oxygenation using noncontact diffuse correlation spectroscopy flow-oximeter.
Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 96 citations in OpenAlex.
- Investigating the Impact of Guided Imagery on Stress, Brain Functions, and Attention: A Randomized Trial.Sensors (Basel, Switzerland) · 2023Trial
- Noninvasive diffuse optical monitoring of cerebral blood flow and oxygenation responses to intermittent hypoxia in neonatal rats.Journal of biomedical optics · 2026Article
- Noncontact diffuse optical imaging of blood flow and oxygenation distributions in reconstructive rat skin flaps.Biomedical optics express · 2025Article
- Acoustomotive diffuse correlation spectroscopy for sensing mechanical stiffness in tissue-mimicking phantoms.Biomedical optics express · 2024Article
- Test-retest reliability of fNIRS in resting-state cortical activity and brain network assessment in stroke patients.Biomedical optics express · 2023Article
- Cerebrovascular impedance estimation with near-infrared and diffuse correlation spectroscopy.Neurophotonics · 2023Article
- Comprehensive investigations of cerebral hemodynamic responses in CSVD patients with mental disorders: a pilot study.Frontiers in psychiatry · 2023Article
- Noninvasive optical monitoring of pulmonary embolism: a Monte Carlo study on visible Chinese human thoracic tissues.Journal of biomedical optics · 2023Article
- Non-invasive optical monitoring of human lungs: Monte Carlo modeling of photon migration in Visible Chinese Human and an experimental test on a human.Biomedical optics express · 2022Article
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- Decoupling channel count from field of view and spatial resolution in single-sensor imaging systems for fluorescence image-guided surgery.Journal of biomedical optics · 2022Article
- Age-related difference in muscle metabolism patterns during upper limb's encircling exercise: a near-infrared spectroscopy study.Biomedical optics express · 2022Article
- Characteristics of frontal activity relevant to cognitive function in bipolar depression: an fNIRS study.Biomedical optics express · 2022Article
- Fast diffuse correlation spectroscopy with a low-cost, fiber-less embedded diode laser.Biomedical optics express · 2021Article
- Extraction of tissue optical property and blood flow from speckle contrast diffuse correlation tomography (scDCT) measurements.Biomedical optics express · 2021Article
- Speckle contrast diffuse correlation tomography of cerebral blood flow in perinatal disease model of neonatal piglets.Journal of biophotonics · 2021Article
- Simultaneous measurements of tissue blood flow and oxygenation using a wearable fiber-free optical sensor.Journal of biomedical optics · 2021Article
- Improved accuracy of cerebral blood flow quantification in the presence of systemic physiology cross-talk using multi-layer Monte Carlo modeling.Neurophotonics · 2021Article
- fNIRS Evaluation of Frontal and Temporal Cortex Activation by Verbal Fluency Task and High-Level Cognition Task for Detecting Anxiety and Depression.Frontiers in psychiatry · 2021Article
- Task and Non-task Brain Activation Differences for Assessment of Depression and Anxiety by fNIRS.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
We report a novel noncontact diffuse correlation spectroscopy flow-oximeter for simultaneous quantification of relative changes in tissue blood flow (rBF) and oxygenation (Δ[oxygenation]). The noncontact probe was compared against a contact probe in tissue-like phantoms and forearm muscles (n = 10), and the dynamic trends in both rBF and Δ[oxygenation] were found to be highly correlated. However, the magnitudes of Δ[oxygenation] measured by the two probes were significantly different. Monte Carlo simulations and phantom experiments revealed that the arm curvature resulted in a significant underestimation (~-20%) for the noncontact measurements in Δ[oxygenation], but not in rBF. Other factors that may cause the residual discrepancies between the contact and noncontact measurements were discussed, and further comparisons with other established technologies are needed to identify/quantify these factors. Our research paves the way for noncontact and simultaneous monitoring of blood flow and oxygenation in soft and vulnerable tissues without distorting tissue hemodynamics.
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