ArticleJournal of neurophysiology2013
A modulatory effect of the feedback from higher visual areas to V1 in the mouse.
Article in Journal of neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Excitatory-inhibitory recurrent dynamics produce robust visual grids and stable attractors.Cell reports · 2022Article
- Distinct organization of two cortico-cortical feedback pathways.Nature communications · 2022Article
- Synaptic properties of the lemniscal and paralemniscal pathways to the mouse somatosensory thalamus.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Stream-dependent development of higher visual cortical areas.Nature neuroscience · 2017Article
- Thalamus plays a central role in ongoing cortical functioning.Nature neuroscience · 2016Review
- Top-Down-Mediated Facilitation in the Visual Cortex Is Gated by Subcortical Neuromodulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Developmental decline in modulation of glutamatergic synapses in layer IV of the barrel cortex by group II metabotropic glutamate receptors.Neuroscience · 2015Article
- Properties of the primary somatosensory cortex projection to the primary motor cortex in the mouse.Journal of neurophysiology · 2015Article
- Modulatory effects of activation of metabotropic glutamate receptors on GABAergic circuits in the mouse thalamus.Journal of neurophysiology · 2015Article
- Article
- NMDA spike/plateau potentials in dendrites of thalamocortical neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Modulatory effects of activation of metabotropic glutamate receptors on GABAergic circuits in the mouse cortex.Journal of neurophysiology · 2014Article
- Treatment of amblyopia in the adult: insights from a new rodent model of visual perceptual learning.Frontiers in neural circuits · 2014Review
- Hierarchical representation of shapes in visual cortex-from localized features to figural shape segregation.Frontiers in computational neuroscience · 2014Article
- Adaptive learning in a compartmental model of visual cortex-how feedback enables stable category learning and refinement.Frontiers in psychology · 2014Article
- Visual cortical areas of the mouse: comparison of parcellation and network structure with primates.Frontiers in neural circuits · 2014Review
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2 authors.
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Abstract
Using a mouse brain slice preparation, we studied the modulatory effects of a feedback projection from higher visual cortical areas, mostly or exclusively area LM (or V2), on two inputs to layer 4 cells in the first visual area (V1). The two inputs to these cells were geniculocortical and an unspecified intracortical input, possibly involving layer 6 cells. We found that activation of metabotropic glutamate receptors (mGluRs) from stimulation of the feedback projection reduced the evoked excitatory postsynaptic currents of both of these inputs to layer 4 but that this modulation acts in an input-specific way. Reducing the strength of the geniculocortical input in adults involved both presynaptic and postsynaptic group I mGluRs (although in younger animals presynaptic group II mGluRs were also involved), whereas modulation of the intracortical input acted entirely via postsynaptic group II mGluRs. These results demonstrate that one of the effects of this feedback pathway is to control the gain of geniculocortical transmission.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.