ArticleClinical and vaccine immunology : CVI2013
Role of gluten intake at the time of hepatitis B virus vaccination in the immune response of celiac patients.
Article in Clinical and vaccine immunology : CVI, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Viruses and celiac disease: what do we know ?Clinical and experimental medicine · 2023Pooled it
- Immune response to Hepatitis B vaccine in patients with celiac disease: A systematic review and meta-analysis.Human vaccines & immunotherapeutics · 2015Pooled it
- No Increased Risk of Hepatitis B Virus Infection in Patients with Celiac Disease: A Population-Based Study.Digestive diseases and sciences · 2025Article
- Viral infections in celiac disease: what should be considered for better management.Clinical and experimental medicine · 2024Review
- Vaccine Efficacy and Safety in Patients with Celiac Disease.Vaccines · 2024Review
- Overview of Hepatitis B Vaccine Non-Response and Associated B Cell Amnesia: A Scoping Review.Pathogens (Basel, Switzerland) · 2024Article
- A Comprehensive Review of Hepatitis B Vaccine Nonresponse and Associated Risk Factors.Vaccines · 2024Review
- COVID-19 and celiac disease: a review.Therapeutic advances in gastroenterology · 2023Review
- Article
- Association between Elevated TGA-IgA Titers and Older Age at Diagnosis with Absence of HBV Seroconversion in Celiac Children.Vaccines · 2021Article
- Vaccinations and Immune Response in Celiac Disease.Vaccines · 2020Review
- Factors That Influence the Immune Response to Vaccination.Clinical microbiology reviews · 2019Review
- Immune response to vaccines in children with celiac disease.World journal of gastroenterology · 2017Review
- Immune response to hepatitis B virus vaccine in celiac subjects at diagnosis.World journal of hepatology · 2016Article
- Extending the Debate on Poor Response to Hepatitis B Virus Vaccination in Children With Celiac Disease: Which Question Remains?Hepatitis monthly · 2015Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Some reports have demonstrated an inadequate response to hepatitis B vaccination in patients affected by celiac disease. The aim of our study was to evaluate hepatitis B vaccination response in relation to gluten exposure status in patients with celiac disease. To measure the gluten exposure status at the time of vaccination, we considered three groups: group A (exposed to gluten), including patients vaccinated as 12-year-old adolescents (the celiac disease diagnosis was established after vaccination); group B (not exposed to gluten), including patients vaccinated as 12-year-old adolescents on a gluten-free diet at the time of vaccination; and group C (infants), including patients vaccinated at birth. The response of celiac patients to hepatitis B vaccination was compared to that of healthy subjects, i.e., those in the control group (group D). This study included 163 celiac patients (group A, 57 patients; group B, 46 patients; and group C, 60 patients) and 48 controls (group D). An inadequate response to hepatitis B immunization was present in 43.9% of patients in group A, 34.8% of patients in group B, 58.3% of patients in group C, and 8.3% of patients in group D (group A versus group D, P < 0.001; group B versus group D, P = 0.002; group C versus group D, P = 0.001) (no significant difference for group A versus group B and group A versus group C was evident). Our data suggest that gluten exposure does not influence the response to hepatitis B immunization and that the human leukocyte antigen probably plays the main immunological role in poor responses to hepatitis B-vaccinated celiac patients.
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