Trial reportBMC medical informatics and decision making2013
Cost effectiveness of a computer-delivered intervention to improve HIV medication adherence.
Trial report in BMC medical informatics and decision making, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01304186 (An Automated, Tailored Information Application for Medication Health Literacy), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Automated, Tailored Information Application for Medication Health Literacy
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- A systematic review of the theory of planned behaviour interventions for chronic diseases in low health-literacy settings.Journal of global health · 2023Pooled it
- Cost-Effectiveness of Anti-retroviral Adherence Interventions for People Living with HIV: A Systematic Review of Decision Analytical Models.Applied health economics and health policy · 2023Pooled it
- Challenges in the Evaluation of Interventions to Improve Engagement Along the HIV Care Continuum in the United States: A Systematic Review.AIDS and behavior · 2017Pooled it
- Acceptance and Commitment to Empowerment Intervention to Reduce HIV Stigma and Promote Community Resilience: Protocol for an Implementation Study.JMIR research protocols · 2026Article
- A mobile app for chronic disease self-management for individuals with low health literacy: A multisite randomized controlled clinical trial.Journal of ageing and longevity · 2024Article
- A mobile app for chronic disease self-management for individuals with low health literacy: A multisite randomized controlled clinical trial.medRxiv : the preprint server for health sciences · 2023Article
- Creating a Tailored Info App to Promote Self-Management Skills in Persons with Chronic Health Conditions: Development Strategies and User Experience.Distance learning (Greenwich, Conn.) · 2023Article
- Article
- Cost-effectiveness of a Medical Care Coordination Program for People With HIV in Los Angeles County.Open forum infectious diseases · 2019Article
- What are the barriers and challenges faced by adolescents when searching for sexual health information on the internet? Implications for policy and practice from a qualitative study.Sexually transmitted infections · 2019Article
- A mixed analysis approach to elucidate the multiple chronic condition experience of English- and Spanish-speaking older adults.Clinical interventions in aging · 2019Article
- Enhancing the Impact of Mobile Health Literacy Interventions to Reduce Health Disparities.Quarterly review of distance education · 2019Article
- A Mobile App for Chronic Disease Self-Management: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2017Article
- Virtual intervention to support self-management of antiretroviral therapy among people living with HIV.Journal of medical Internet research · 2015Article
- Cost-effectiveness analysis along the continuum of HIV care: how can we optimize the effect of HIV treatment as prevention programs?Current HIV/AIDS reports · 2014Review
- Development of a culturally appropriate computer-delivered tailored Internet-based health literacy intervention for Spanish-dominant Hispanics living with HIV.BMC medical informatics and decision making · 2014Article
- Commentary: demonstrating cost-effectiveness in pediatric psychology.Journal of pediatric psychology · 2014Article
- Negative and positive beliefs related to mood and health.American journal of health behavior · 2014Article
- Health literacy: impact on the health of HIV-infected individuals.Current HIV/AIDS reports · 2013Review
- Development and initial validation of a computer-administered health literacy assessment in Spanish and English: FLIGHT/VIDAS.Patient related outcome measures · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundHigh levels of adherence to medications for HIV infection are essential for optimal clinical outcomes and to reduce viral transmission, but many patients do not achieve required levels. Clinician-delivered interventions can improve patients' adherence, but usually require substantial effort by trained individuals and may not be widely available. Computer-delivered interventions can address this problem by reducing required staff time for delivery and by making the interventions widely available via the Internet. We previously developed a computer-delivered intervention designed to improve patients' level of health literacy as a strategy to improve their HIV medication adherence. The intervention was shown to increase patients' adherence, but it was not clear that the benefits resulting from the increase in adherence could justify the costs of developing and deploying the intervention. The purpose of this study was to evaluate the relation of development and deployment costs to the effectiveness of the intervention.
methodsCosts of intervention development were drawn from accounting reports for the grant under which its development was supported, adjusted for costs primarily resulting from the project's research purpose. Effectiveness of the intervention was drawn from results of the parent study. The relation of the intervention's effects to changes in health status, expressed as utilities, was also evaluated in order to assess the net cost of the intervention in terms of quality adjusted life years (QALYs). Sensitivity analyses evaluated ranges of possible intervention effectiveness and durations of its effects, and costs were evaluated over several deployment scenarios.
resultsThe intervention's cost effectiveness depends largely on the number of persons using it and the duration of its effectiveness. Even with modest effects for a small number of patients the intervention was associated with net cost savings in some scenarios and for durations greater than three months and longer it was usually associated with a favorable cost per QALY. For intermediate and larger assumed effects and longer durations of intervention effectiveness, the intervention was associated with net cost savings.
conclusionsComputer-delivered adherence interventions may be a cost-effective strategy to improve adherence in persons treated for HIV.
trial registrationClinicaltrials.gov identifier NCT01304186.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.