ArticleJournal of musculoskeletal & neuronal interactions2013
Electrical impedance alterations in the rat hind limb with unloading.
Article in Journal of musculoskeletal & neuronal interactions, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Estrogen Receptor Alpha (ERα) Is Involved in Resveratrol-Mediated Muscle Preservation During Mechanical Unloading in Male Rats.Muscles (Basel, Switzerland) · 2026Article
- A comparison of electromyography techniques: surface versus intramuscular recording.European journal of applied physiology · 2025Review
- Electrical impedance myography detects age-related skeletal muscle atrophy in adult zebrafish.Scientific reports · 2023Article
- Immediate Effects of Functional Electrical Stimulation-Assisted Cycling on the Paretic Muscles of Patients With Hemiparesis After Stroke: Evidence From Electrical Impedance Myography.Frontiers in aging neuroscience · 2022Article
- Potential Utility of Electrical Impedance Myography in Evaluating Age-Related Skeletal Muscle Function Deficits.Frontiers in physiology · 2021Review
- Approaching Gravity as a Continuum Using the Rat Partial Weight-Bearing Model.Life (Basel, Switzerland) · 2020Review
- Using Electrical Impedance Myography as a Biomarker of Muscle Deconditioning in Rats Exposed to Micro- and Partial-Gravity Analogs.Frontiers in physiology · 2020Article
- Partial Weight-Bearing in Female Rats: Proof of Concept in a Martian-Gravity Analog.Frontiers in physiology · 2020Article
- Electrical Impedance Methods in Neuromuscular Assessment: An Overview.Cold Spring Harbor perspectives in medicine · 2019Review
- Pitfalls in the measurement of muscle mass: a need for a reference standard.Journal of cachexia, sarcopenia and muscle · 2018Article
- Predicting myofiber size with electrical impedance myography: A study in immature mice.Muscle & nerve · 2018Article
- Electrical impedance myography for assessment of Duchenne muscular dystrophy.Annals of neurology · 2017Article
- Article
- Electrical Impedance Myography and Its Applications in Neuromuscular Disorders.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2017Review
- Localized Electrical Impedance Myography of the Biceps Brachii Muscle during Different Levels of Isometric Contraction and Fatigue.Sensors (Basel, Switzerland) · 2016Article
- The neuromuscular impact of symptomatic SMN restoration in a mouse model of spinal muscular atrophy.Neurobiology of disease · 2016Article
- Differentiation of the intracellular structure of slow- versus fast-twitch muscle fibers through evaluation of the dielectric properties of tissue.Physics in medicine and biology · 2014Article
- The effect of profound dehydration on electrical impedance of mouseskeletal muscle.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2014Article
- Spaceflight and hind limb unloading induce similar changes in electrical impedance characteristics of mouse gastrocnemius muscle.Journal of musculoskeletal & neuronal interactions · 2013Article
- Single and modeled multifrequency electrical impedance myography parameters and their relationship to force production in the ALS SOD1G93A mouse.Amyotrophic lateral sclerosis & frontotemporal degenerationArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectivesMethods are needed for quantifying muscle deconditioning due to immobilization, aging, or spaceflight. Electrical impedance myography (EIM) is one technique that may offer easy-to-follow metrics. Here, we evaluate the time course and character of the change in single- and multi-frequency EIM parameters in the hind-limb suspension model of muscle deconditioning in rats.
methodsSixty-two rats were studied with EIM during a two-week period of hind limb unloading followed by a two-week recovery period. Random subsets of animals were sacrificed at one-week time intervals to measure muscle fiber size.
resultsSignificant alterations were observed in nearly all impedance parameters. The 50 kHz phase and multi-frequency phase-slope, created by taking the slope of a line fitted to the impedance values between 100-500 kHz, appeared most sensitive to disuse atrophy, the latter decreasing by over 33.0±6.6% (p<0.001), a change similar to the maximum reduction in muscle fiber size. Impedance alterations, however, lagged changes in muscle fiber size.
conclusionsEIM is sensitive to disuse change in the rat, albeit with a delay relative to alterations in muscle fiber size. Given the rapidity and simplicity of EIM measurements, the technique could prove useful in providing a non-invasive approach to measuring disuse change in animal models and human subjects.
Indexed as
Identifiers
23445913PMC3984464What OpenQuestion holds
Registered trials
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