ArticleWorld journal of surgical oncology2013
Routine use of positron-emission tomography/computed tomography for staging of primary colorectal cancer: does it affect clinical management?
Article in World journal of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Colon cancer: the 2023 Korean clinical practice guidelines for diagnosis and treatment.Annals of coloproctology · 2024Guideline
- Surgery with versus without preoperative concurrent chemoradiotherapy for mid/low rectal cancer: an interim analysis of a prospective, randomized trial.Chinese journal of cancer · 2015Trial
- Positron emission tomography/computed tomography for optimized colon cancer staging and follow up.Scandinavian journal of gastroenterology · 2014Trial
- Colorectal liver metastases: Current management and future perspectives.World journal of clinical oncology · 2020Review
- Patterns of recurrence in patients achieving pathologic complete response after neoadjuvant chemoradiotherapy for rectal cancer.Journal of cancer research and clinical oncology · 2017Article
- Diagnostic and prognostic value of preoperativeIntestinal research · 2017Article
- Assessment and diagnostic accuracy of lymph node status to predict stage III colon cancer using computed tomography.Cancer imaging : the official publication of the International Cancer Imaging Society · 2017Article
- Pre-operative TNM staging of primary colorectal cancer by (18)F-FDG PET-CT or PET: a meta-analysis including 2283 patients.International journal of clinical and experimental medicine · 2015Article
- The role of positron emission tomography/computed tomography in the initial staging of colon cancer.Annals of coloproctology · 2014Article
- The role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the primary staging of rectal cancer.World journal of surgical oncology · 2014Article
- Positron emission tomography/computed tomography in the staging of colon cancer.Annals of coloproctology · 2014Article
- Clinical impact of FDG-PET/CT on colorectal cancer staging and treatment strategy.American journal of nuclear medicine and molecular imaging · 2014Article
- Imaging in rectal cancer with emphasis on local staging with MRI.The Indian journal of radiology & imagingArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of positron emission tomography-computed tomography (PET/CT) for the preoperative staging of patients with colon and rectal cancer has increased steadily over the last decade. The aim of this study was to evaluate the effect of PET/CT on the preoperative staging and clinical management of patients with colorectal cancer.
methodsBetween December 2010 and February 2012, 64 consecutive patients with colorectal cancer were evaluated with both PET/CT scans and conventional preoperative imaging studies. We prospectively recorded the medical reports of these patients. The PET/CT findings were compared with conventional imaging studies and the rate of over-staging or down-staging and changes in clinical management were evaluated. The correlation of the PET/CT with the conventional imaging was compared by a kappa agreement coefficient. Differences in the accuracy for N and T staging were assessed by χ2 and related-samples marginal homogeneity tests.
resultsThirty-nine (60.9%) patients had rectal cancer and 25 (39.1%) had colon cancer. Based on PET/CT, additional lesions were found in 6 (9.4%) of the patients: hilar and paratracheal lesions in 4 patients, hepatic in 1 and supraclavicular in 1 patient. In four of six patients, detailed imaging studies or biopsies revealed chronic inflammatory changes. Hepatic and supraclavicular involvement was confirmed in two patients. Therefore, the false positivity rate of PET/CT was 6.25%. Based on the additional PET/CT, 2 (3.2%) patients had a change in surgical management. A chemotherapy regimen was administered to the patient with a 1.5 cm hepatic metastasis near the right hepatic vein; for another patient with an identified supraclavicular lymph node metastasis, a simultaneous excision was performed.
conclusionsRoutine use of PET/CT for preoperative staging did not impact disease management for 96.8% of our patients. The results of our study conclude that PET/CT should not be routinely used for primary staging of colorectal cancer. More studies are required for identifying the subgroup of patients who might benefit from a PET/CT in their initial staging.
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