Evidence map›Paper›PMID 23445513›Full record

ArticleChronobiology international2013

Season of birth is associated with adult body mass index in patients with bipolar disorder.

Isabella Soreca, Yu Cheng, Ellen Frank, Andrea Fagiolini, David J Kupfer

Open access · greenAbstract read
In one paragraph

Article in Chronobiology international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Longitudinal Growth Patterns in Boys and Girls Aged 9-14 Years by Birth Season.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
  3. Article
  4. Birth Month and Course of Recurrent Depressive Disorders in a Polish Population.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Isabella SorecaDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA. sorecai@upmc.edu
Yu Cheng
Ellen Frank
Andrea Fagiolini
David J Kupfer
University of Pittsburgh · USUniversity of Siena · IT

Funding

Depression: The Search for Treatment-Relevant PhenotypesR01MH065376 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRANK, ELLEN · 2003 to 2009
$4.0M
NIMH NIH HHS MH065376NIMH NIH HHS R01 MH065376
6 · The paper itself

Abstract

Cardiovascular risk factors, such as abdominal obesity and obesity in general, are very prevalent among patients with bipolar disorder (BD). Although long-term use of psychotropic medications is an important determinant of these risk factors, other evidence suggests that early development may interact with the mood disorder diathesis to exponentially increase the risk of obesity. The goal of our study was to test whether season of birth is associated with adult body mass index (BMI) and abdominal obesity in individuals with bipolar disorder. We compared season of birth effects on BMI in 375 adult patients with bipolar disorder and 196 adult patients with unipolar major depression. We found a significant season of birth effect on BMI in patients with bipolar disorder, but not unipolar. In patients with bipolar disorder, season of birth was also associated with waist circumference, with a stronger effect in males. Season of birth affects adult BMI and waist circumference in patients with bipolar disorder, but not in patients with unipolar depression. Our results suggest that early environmental factors, yet to be identified, interact with specific neurobiological features of bipolar disorder to determine stable traits and disease risk factors in adult life.

Indexed as

Body Mass IndexSeasonsAdultAgingBipolar DisorderFemaleHumansMajor Depressive DisorderMale

Identifiers

PMID23445513
PMCPMC4254801
OpenAlexW1992864930

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.