ArticleCroatian medical journal2013
Mitochondrial and Y-chromosomal profile of the Kazakh population from East Kazakhstan.
Article in Croatian medical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- First follicular fluid cf-mtDNA sequencing unveils ovarian stimulation-induced mutations impacting oocyte quality and IVF success.Journal of assisted reproduction and genetics · 2025Article
- Kazak mitochondrial genomes provide insights into the human population history of Central Eurasia.PloS one · 2022Article
- Whole-Genome Sequencing and Genomic Variant Analysis of Kazakh Individuals.Frontiers in genetics · 2022Article
- Forensic features and genetic legacy of the Baloch population of Pakistan and the Hazara population across Durand line revealed by Y-chromosomal STRs.International journal of legal medicine · 2021Article
- Genetic Relationship Among the Kazakh People Based on Y-STR Markers Reveals Evidence of Genetic Variation Among Tribes and Zhuz.Frontiers in genetics · 2021Article
- Association of polymorphisms in TP53 and the promoter region of IL10 with gastric cancer in a Kazakh population.Bosnian journal of basic medical sciences · 2020Article
- Y-chromosome evidence confirmed the Kerei-Abakh origin of Aksay Kazakhs.Journal of human genetics · 2020Article
- Decoding a highly mixed Kazakh genome.Human genetics · 2020Article
- Development of the Kazakhstan Y-chromosome haplotype reference database: analysis of 27 Y-STR in Kazakh population.International journal of legal medicine · 2019Article
- Type 2 diabetes mellitus: distribution of genetic markers in Kazakh population.Clinical interventions in aging · 2018Article
- The Connection of the Genetic, Cultural and Geographic Landscapes of Transoxiana.Scientific reports · 2017Article
- Analysis of genetic admixture in Uyghur using the 26 Y-STR loci system.Scientific reports · 2016Article
- Polymorphisms in genes involved in the absorption, distribution, metabolism, and excretion of drugs in the Kazakhs of Kazakhstan.BMC genetics · 2016Article
- Global mobility and the break-up of human population isolates - neglected mechanisms in health, demographics, and anthropology.Croatian medical journal · 2015Article
- Genetic polymorphism of 17 Y chromosomal STRs in Kazakh and Uighur populations from Xinjiang, China.International journal of legal medicine · 2014Article
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7 authors.
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Abstract
aimTo study the genetic relationship of Kazakhs from East Kazakhstan to other Eurasian populations by examining paternal and maternal DNA lineages.
methodsWhole blood samples were collected in 2010 from 160 unrelated healthy Kazakhs residing in East Kazakhstan. Genomic DNA was extracted with Wizard genomic DNA Purification Kit. Nucleotide sequence of hypervariable segment I of mitochondrial DNA (mtDNA) was determined and analyzed. Seventeen Y-short tandem repeat (STR) loci were studied in 67 samples with the AmpFiSTR Y-filer PCR Amplification Kit. In addition, mtDNA data for 2701 individuals and Y-STR data for 677 individuals were retrieved from the literature for comparison.
resultsThere was a high degree of genetic differentiation on the level of mitochondrial DNA. The majority of maternal lineages belonged to haplogroups common in Central Asia. In contrast, Y-STR data showed very low genetic diversity, with the relative frequency of the predominant haplotype of 0.612.
conclusionThe results revealed different migration patterns in the population sample, showing there had been more migration among women. mtDNA genetic diversity in this population was equivalent to that in other Central Asian populations. Genetic evidence suggests the existence of a single paternal founder lineage in the population of East Kazakhstan, which is consistent with verbal genealogical data of the local tribes.
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