ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2013
Comparison of contemporaneous left ventricular ejection fraction (LVEF) obtained from planar gated cardiac blood pool scans (GCBPS) and Tl-201 gated myocardial perfusion scans (MPS) using a novel solid state dedicated cardiac camera.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Tl-201 dosing for CZT SPECT: More new information.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited data on the concordance of left ventricular ejection fraction (LVEF) obtained via solid state dedicated cardiac cameras (SSD) and gated cardiac blood pool scans (GCBPS). This study aimed to examine the agreement of LVEF measured during GCBPS and Tl-201 myocardial perfusion scans (MPS) using SSD.
methodsSeventy six patients were enrolled. Following stress MPS with 0.8 Mbq/kg (0.022 mCi/kg) Tl-201 and 8-frame gated rest studies after additional 15 Mbq (0.41 mCi) Tl-201, LVEFs were obtained using ECToolbox (ECT) and quantitative gated SPECT (QGS) software. Same day 16-frame planar GCBPS were performed. Interobserver variability was compared and LVEF results were compared using paired t tests, Pearson's correlation and the differences of the LVEF were plotted against GCBPS values.
resultsFor GCBPS, ECT and QGS, the mean (±SD) LVEF was 52% ± 14%, 61% ± 18% and 48% ± 19%, respectively. When compared to GCBPS, ECT and QGS, LVEFs had similar R values of 0.85 and 0.83, respectively, and mean differences [95% limits of agreement (LA)] of -8.6% (-27.4% to +10.2%, P < .001) and 4.2% (-17.2% to +25.6%, P = .001), respectively.
conclusionWhile the LVEF obtained by ECT or QGS demonstrates a statistically significant correlation with GCBPS, they are significantly different and the wide 95% LA suggest that Tl-201 MPS LVEFs derived from either software package are not interchangeable with GCBPS results.
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