ArticleBritish journal of cancer2013
Fecal microbiota diversity in survivors of adolescent/young adult Hodgkin lymphoma: a study of twins.
Article in British journal of cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The gut microbiome, symptoms, and targeted interventions in children with cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Pooled it
- Role of the gut microbiome in the development and prognosis of pediatric leukemia.World journal of clinical oncology · 2025Review
- Gut microbiota-derived extracellular vesicles form a distinct entity from gut microbiota.mSystems · 2025Article
- Gut microbiota plays pivotal roles in benign and malignant hematopoiesis.Blood science (Baltimore, Md.) · 2024Review
- Review of the microbiome and metabolic pathways associated with psychoneurological symptoms in children with cancer.Asia-Pacific journal of oncology nursing · 2024Review
- How aging influences the gut-bone marrow axis and alters hematopoietic stem cell regulation.Heliyon · 2024Review
- The causal relationship between gut microbiota and lymphoma: a two-sample Mendelian randomization study.Frontiers in immunology · 2024Article
- Probiotics: Potential Benefits and Safety in Hematological Malignancies.Galen medical journal · 2024Review
- Intestinal Microbes and Hematological Malignancies.Cancers · 2023Review
- Role of the gut microbiota in hematologic cancer.Frontiers in microbiology · 2023Review
- Integration analysis of tumor metagenome and peripheral immunity data of diffuse large-B cell lymphoma.Frontiers in immunology · 2023Article
- Fecal microbiota of adolescent and young adult cancer survivors and metabolic syndrome: an exploratory study.Pediatric hematology and oncology · 2022Article
- Gut dysbiosis in cutaneous T-cell lymphoma is characterized by shifts in relative abundances of specific bacterial taxa and decreased diversity in more advanced disease.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022Article
- The gut microbiome in patients with chronic lymphocytic leukemia.Haematologica · 2022Article
- Microbiome Profile of Dogs with Stage IV Multicentric Lymphoma: A Pilot Study.Veterinary sciences · 2022Article
- Association of antibiotic-consumption patterns with the prevalence of hematological malignancies in European countries.Scientific reports · 2022Article
- How to Maintain a Healthy Gut Microbiome in Children with Cancer? Gut Microbiome Association with Diet in Children with Solid Tumors Postchemotherapy.Omics : a journal of integrative biology · 2022Article
- The Role of Microbiota in the Development of Cancer Tumour Cells and Lymphoma of B and T Cells.Cureus · 2021Review
- Review
- Gut Microbiota Influence in Hematological Malignancies: From Genesis to Cure.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundAdolescent/young adult Hodgkin lymphoma (AYAHL) survivors report fewer exposures to infections during childhood compared with controls, and they have functional lymphocyte aberrations. The gut microbiota plays a central role in immunity.
methodsWe investigated whether fecal microbial diversity differed between 13 AYAHL survivors and their unaffected co-twin controls. Pyrosequencing of fecal bacterial 16S rRNA amplicons yielded 252 943 edited reads that were assigned to species-level operational taxonomic units (OTUs) and standardised for sequencing depth by random sampling. Microbial diversity was compared within vs between twin pairs and by case-control status.
resultsThe number of unique OTUs was more similar within twin pairs compared with randomly paired participants (P=0.0004). The AYAHL cases had fewer unique OTUs compared with their co-twin controls (338 vs 369, P=0.015); this difference was not significant (169 vs 183, P=0.10) when restricted to abundant OTUs.
conclusionIn this small study, AYAHL survivors appear to have a deficit of rare gut microbes. Further work is needed to determine if reduced microbial diversity is a consequence of the disease, its treatment, or a particularly hygienic environment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.