Evidence map›Paper›PMID 23443386›Full record

ArticleSensors (Basel, Switzerland)2012

Applications of surface plasmon resonance (SPR) for the characterization of nanoparticles developed for biomedical purposes.

Mara Canovi, Jacopo Lucchetti, Matteo Stravalaci, Francesca Re, Davide Moscatelli, Paolo Bigini, Mario Salmona, Marco Gobbi

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. AdvancingACS bio & med chem Au · 2024
    Review
  4. Article
  5. Article
  6. Chemical Sensor Nanotechnology in Pharmaceutical Drug Research.Nanomaterials (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mara CanoviDepartment of Biochemistry and Molecular Pharmacology, Mario Negri Institute for Pharmacological Research, Milano 20156, Italy. mara.canovi@marionegri.it
Jacopo Lucchetti
Matteo Stravalaci
Francesca Re
Davide Moscatelli
Paolo Bigini
Mario Salmona
Marco Gobbi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Great interest is currently being devoted to the development of nanoparticles (NPs) for biomedical purposes, designed to improve the pharmacokinetic profile of their cargos (either imaging probes or drugs) and to enhance the specific targeting at the disease site. Recent works suggest that Surface Plasmon Resonance (SPR), widely used for the analysis of biomolecular interactions, represents a technique of choice for rapid and quantitative analyses of the interaction between NPs--functionalized with specific ligands--and their putative biological targets. Moreover, SPR can provide important details on the formation and the role of the protein "corona", i.e., the protein layer which coats NPs once they come into contact with biological fluids. These novel applications of SPR sensors may be very useful to characterize, screen and develop nanodevices for biomedical purposes.

Indexed as

Biosensing TechniquesSurface Plasmon ResonanceHumansLigandsNanoparticlesLigands

Identifiers

PMID23443386
PMCPMC3571790

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.