Evidence map›Paper›PMID 23443043›Full record

ReviewCardiology in the young2013

MicroRNAs: a new piece in the paediatric cardiovascular disease puzzle.

Ahmed Omran, Dalia Elimam, Keith A Webster, Lina A Shehadeh, Fei Yin

Abstract readReview
In one paragraph

Review in Cardiology in the young, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. miRNAs in Heart Development and Disease.International journal of molecular sciences · 2024
    Review
  3. Posttranscriptional Regulation by Proteins and Noncoding RNAs.Advances in experimental medicine and biology · 2024
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Role of microRNAs in cardiac development and disease.Experimental and therapeutic medicine · 2017
    Article
  10. MicroRNAs in congenital heart disease.Annals of translational medicine · 2015
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed OmranDepartment of Pediatrics and Neonatology, Suez Canal University, Ismailia, Egypt.
Dalia Elimam
Keith A Webster
Lina A Shehadeh
Fei Yin

Funding

Regulated Therapeutic Angiogenesis: for Ischemic DiseaseR01HL072924 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI WEBSTER, KEITH A · 2003 to 2014
$3.2M
Mechanisms for miR-30e Regulated Atherogenic Pathways with AgeK01AG040468 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SHEHADEH, LINA A · 2012 to 2014
$365k
NHLBI NIH HHS R01 HL072924NIA NIH HHS K01 AG040468
6 · The paper itself

Abstract

Cardiovascular diseases in children comprise a large public health problem. The major goals of paediatric cardiologists and paediatric cardiovascular researchers are to identify the cause(s) of these diseases to improve treatment and preventive protocols. Recent studies show the involvement of microRNAs (miRs) in different aspects of heart development, function, and disease. Therefore, miR-based research in paediatric cardiovascular disorders is crucial for a better understanding of the underlying pathogenesis of the disease, and unravelling novel, efficient, preventive, and therapeutic means. The ultimate goal of such research is to secure normal cardiac development and hence decrease disabilities, improve clinical outcomes, and decrease the morbidity and mortality among children. This review focuses on the role of miRs in different paediatric cardiovascular conditions in an effort to encourage miR-based research in paediatric cardiovascular disorders.

Indexed as

Arrhythmias, CardiacCardiomyopathiesCardiovascular DiseasesChildHeart Defects, CongenitalHeart FailureHumansMetabolic SyndromeMicroRNAsMyocarditisStem CellsMicroRNAs

Identifiers

PMID23443043
PMCPMC3748175

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.