ArticleHealth and quality of life outcomes2013
Measuring global health-related quality of life in children undergoing hematopoietic stem cell transplant: a longitudinal study.
Article in Health and quality of life outcomes, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Patient-reported outcomes in Hodgkin lymphoma trials: a systematic review.Frontiers in oncology · 2024Pooled it
- Nonmyeloablative HLA-identical sibling transplant for sickle cell disease in children: a multicenter prospective study.Blood advances · 2026Trial
- Group-based trajectories of health-related quality of life among pediatric patients with high-risk Hodgkin lymphoma.Journal of the National Cancer Institute · 2025Trial
- Longitudinal Health-Related Quality of Life Among Patients With High-Risk Pediatric Hodgkin Lymphoma Treated on the Children's Oncology Group AHOD 1331 Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Trial
- Music therapy supported the health-related quality of life for children undergoing haematopoietic stem cell transplants.Acta paediatrica (Oslo, Norway : 1992) · 2018Trial
- Trajectories of Health-Related Quality of Life Among Children With Newly Diagnosed Epilepsy.Journal of pediatric psychology · 2016Trial
- Parent Outlook: How Parents View the Road Ahead as They Embark on Hematopoietic Stem Cell Transplantation for Their Child.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2016Trial
- Performance of the FACT-GOG-Ntx to assess chemotherapy-induced peripheral neuropathy (CIPN) in pediatric high risk Hodgkin lymphoma: report from the Children's Oncology Group AHOD 1331 study.Journal of patient-reported outcomes · 2023Article
- Impact of health-related quality of life on pediatric patients who underwent hematopoietic stem cell transplantation in a Colombian institutionBiomedica : revista del Instituto Nacional de Salud · 2022Article
- Health-related quality of life predicts length of hospital stay and survival rates for pediatric patients receiving allogeneic hematopoietic cell transplantation.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Comparisons.Journal of health economics and outcomes research · 2021Article
- Article
- Understanding the Relationship Between Child Health-Related Quality of Life and Parent Emotional Functioning in Pediatric Hematopoietic Stem Cell Transplant.Journal of pediatric psychology · 2017Article
- Leveraging pediatric PROMIS item banks to assess physical functioning in children at risk for severe functional loss.Journal of patient-reported outcomes · 2017Article
- The impact of pediatric blood and marrow transplant on parents: introduction of the parent impact scale.Health and quality of life outcomes · 2015Article
- Joint models for predicting transplant-related mortality from quality of life data.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015Article
- Predicting Health Care Utilization for Children With Respiratory Insufficiency Using Parent-Proxy Ratings of Children's Health-Related Quality of Life.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & PractitionersArticle
- Health-Related Quality of Life among Children and Adolescents during Hematopoietic Stem Cell Transplant Recovery.Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology NursesArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPediatric health-related quality of life (HRQL) measures explore multiple domains of HRQL. To ease administration, burden, and implementation, we created a 7-item unidimensional global HRQL scale for children. This paper evaluates the psychometric properties of the global HRQL scale in children undergoing hematopoietic stem cell transplant (HSCT) and describes the trajectory of global HRQL scores over the 12-month course following HSCT.
methodsAs part of two longitudinal HSCT studies, HRQL was collected on 312 parent-child dyads using the Child Health Ratings Inventories. Parents of children aged 5-18 completed the pediatric global HRQL scale about their child and 117 adolescents completed the scale themselves. Psychometric properties were compared across both raters. Two repeated measures models were built to describe trajectories of (1) global HRQL for all children based on parent proxy report and (2) global HRQL for adolescents based on adolescent self-report and parent proxy report.
resultsInternal consistency reliability was high for parent proxy report and adolescent self-report (Cronbach's alpha 0.9, 0.8, respectively). Unidimensionality was verified using principal components analysis. Both models indicated decreased global HRQL in the presence of early complications related to HSCT and Model 1 further indicated decreased HRQL in the presence of later complications. Model 2 showed that parent proxies reported lower global HRQL scores than adolescent self-report.
conclusionsThis study has demonstrated the unidimensionality and strong psychometric properties of a 7-item global HRQL scale in a sample of children undergoing HSCT. Despite its brevity, scale scores vary in clinically meaningful ways. Future applications of this scale are encouraged.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.