ReviewBiochemistry2013
Sum of the parts: mass spectrometry-based metabolomics.
Review in Biochemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity.Science (New York, N.Y.) · 2026Article
- Mitochondrial proteostasis regulated by CRL5Communications biology · 2025Article
- Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis.Cell · 2025Article
- Toxicity assessment of VX in zebrafish: multi-organ toxicity evaluation and tissue distribution visualization using DESI-MSI.Archives of toxicology · 2025Article
- High-throughput MALDI-MSI metabolite analysis of plant tissue microarrays.Plant biotechnology journal · 2023Article
- Loss of CD4Immunity · 2023Article
- Dose-Response Metabolomics To Understand Biochemical Mechanisms and Off-Target Drug Effects with the TOXcms Software.Analytical chemistry · 2020Article
- Systems-level analysis of isotopic labeling in untargeted metabolomic data by XNature protocols · 2019Article
- A Protocol to Compare Methods for Untargeted Metabolomics.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Ratiometric quantitation of thiol metabolites using non-isotopic mass tags.Analytica chimica acta · 2018Article
- Systems-Level Annotation of a Metabolomics Data Set Reduces 25 000 Features to Fewer than 1000 Unique Metabolites.Analytical chemistry · 2017Article
- Metabolite Measurement: Pitfalls to Avoid and Practices to Follow.Annual review of biochemistry · 2017Review
- Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health.Frontiers in microbiology · 2016Review
- Metabolomic Analysis Provides Insights on Paraquat-Induced Parkinson-Like Symptoms in Drosophila melanogaster.Molecular neurobiology · 2016Article
- Metabolomics and Its Application to Acute Lung Diseases.Frontiers in immunology · 2016Review
- Omics-Based Biomarkers: Application of Metabolomics in Neuropsychiatric Disorders.The international journal of neuropsychopharmacology · 2015Review
- Neutral and Phospholipids of the Myxococcus xanthus Lipodome during Fruiting Body Formation and Germination.Applied and environmental microbiology · 2015Article
- Correction of precursor and product ion relative abundances in order to standardize CID spectra and improve EcomMetabolomics : Official journal of the Metabolomic Society · 2015Article
- Metabolomic Analysis of Oxidative and Glycolytic Skeletal Muscles by Matrix-Assisted Laser Desorption/IonizationMass Spectrometric Imaging (MALDI MSI).Journal of the American Society for Mass Spectrometry · 2015Article
- Avoiding misannotation of in-source fragmentation products as cellular metabolites in liquid chromatography-mass spectrometry-based metabolomics.Analytical chemistry · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Metabolomics is a rapidly growing field of research used in the identification and quantification of the small molecule metabolites within an organism, thereby providing insights into cell metabolism and bioenergetics as well as processes important in clinical medicine, such as disposition of pharmaceutical compounds. It offers comprehensive information about thousands of low-molecular mass compounds (<1500 Da) that represent a wide range of pathways and intermediary metabolism. Because of its vast expansion in the past two decades, mass spectrometry has become an indispensable tool in "omic" analyses. The use of different ionization techniques such as the more traditional electrospray and matrix-assisted laser desorption, as well as recently popular desorption electrospray ionization, has allowed the analysis of a wide range of biomolecules (e.g., peptides, proteins, lipids, and sugars), and their imaging and analysis in the original sample environment in a workup free fashion. An overview of the current state of the methodology is given, as well as examples of application.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.