ReviewMolecular reproduction and development2013
Polyunsaturated fatty acid derived signaling in reproduction and development: insights from Caenorhabditis elegans and Drosophila melanogaster.
Review in Molecular reproduction and development, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
53 citing papers in PubMed, 115 citations in OpenAlex.
- Weaponizing nutrition: plants use a double strategy to fight herbivory, converting nutritionally essential fatty acids into defensive oxylipin signals.The New phytologist · 2026Article
- Functional Characterization of Fad Genes from Two Chemosymbiotic Bivalves Inhabiting the Haima Cold Seep.Genes · 2026Article
- Polyunsaturated fatty acid and oxylipin profiles of Angiostrongylus cantonensis during cerebral-to-pulmonary migration illuminate parasite and host microenvironmental lipid signatures.Parasites & vectors · 2026Article
- Mating regulates growth, metabolism, and digestive efficiency in the femaleProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Lipids in Insect Reproduction: Where, How, and Why.Advances in experimental medicine and biology · 2026Review
- Octopamine instructs head direction plasticity.bioRxiv : the preprint server for biology · 2025Article
- Forward genetics ineLife · 2025Article
- An inducible and reversible system to regulate unsaturated fatty acid biosynthesis in C. elegans.G3 (Bethesda, Md.) · 2025Article
- Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition.BMC genomics · 2025Article
- Altered plasma fatty acids composition in autism spectrum disorder: a case-control study.Frontiers in psychiatry · 2025Article
- Stage-specific metabolic allocation: nutrient investment strategies duringFrontiers in nutrition · 2025Article
- Maternal lipid mobilization is essential for embryonic development in the malaria vector Anopheles gambiae.PLoS biology · 2024Article
- Multi-Omics Reveals the Role of Arachidonic Acid Metabolism in the Gut-Follicle Axis for the Antral Follicular Development of Holstein Cows.International journal of molecular sciences · 2024Article
- Prostaglandin A3 regulates the colony development ofCrop health · 2024Article
- Modulatory actions ofFrontiers in cellular and infection microbiology · 2024Article
- Quantitative Profiling Method for Oxylipins in Neurodegenerative Diseases by Liquid Chromatography Coupled with Tandem Mass Spectrometry.bioRxiv : the preprint server for biology · 2023Article
- Fatty acid- and retinol-binding protein 6 does not control worm fatty acid content in Caenorhabditis elegans but might play a role in Haemonchus contortus parasitism.Parasites & vectors · 2023Article
- Capillary electrophoresis-mass spectrometry as a tool for Caenorhabditis elegans metabolomics research.Metabolomics : Official journal of the Metabolomic Society · 2023Article
- Omega-3 versus Omega-6: Are We Underestimating the Ecological Significance of Arachidonic Acid in Aquatic Systems?Biomolecules · 2023Article
- Lipidomic Profiling Reveals Concerted Temporal Patterns of Functionally Related Lipids inMetabolites · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Polyunsaturated fatty acids (PUFAs) exhibit a diverse range of critical functions in biological systems. PUFAs modulate the biophysical properties of membranes and, along with their derivatives, the eicosanoids and endocannabinoids, form a wide array potent lipid signaling molecules. Much of our early understanding of PUFAs and PUFA-derived signaling stems from work in mammals; however, technological advances have made comprehensive lipid analysis possible in small genetic models such as Caenorhabditis elegans and Drosophila melanogaster. These models have a number of advantages, such as simple anatomy and genome-wide genetic screening techniques, which can broaden our understanding of fatty-acid-derived signaling in biological systems. Here we review what is known about PUFAs, eicosanoids, and endocannabinoids in the development and reproduction of C. elegans and D. melanogaster. Fatty acid signaling appears to be fundamental for multicellular organisms, and simple invertebrates often employ functionally similar pathways. In particular, studies in C. elegans and Drosophila are providing insight into the roles of PUFAs and PUFA-derived signaling in early developmental processes, such as meiosis, fertilization, and early embryonic cleavage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.