Evidence map›Paper›PMID 23440538›Full record

ReviewCurrent HIV/AIDS reports2013

Antiretroviral drug regimens to prevent mother-to-child transmission of HIV: a review of scientific, program, and policy advances for sub-Saharan Africa.

Benjamin H Chi, Jeffrey S A Stringer, Dhayendre Moodley

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03200054 (Postpartum Adherence Clubs for Antiretroviral Therapy), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03200054 nacompletednot on this mapstarted 2016, after this paper: background citation

Postpartum Adherence Clubs for Antiretroviral Therapy: a Randomised Controlled Trial

TypeinterventionalSponsorUniversity of Cape TownRan2016 to 2020Enrolled412ConditionsHivArmsAdherence Clubs
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Benjamin H ChiCentre for Infectious Disease Research in Zambia, Lusaka, Zambia. bchi@cidrz.org
Jeffrey S A Stringer
Dhayendre Moodley
Centre for Infectious Disease Research in Zambia · ZMCentre for the AIDS Programme of Research in South Africa · ZAUniversity of North Carolina at Chapel Hill · US

Funding

Validation of a community survey methodology for measuring PMTCT impactR01HD075131 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2013
$903k
NICHD NIH HHS R01 HD075131
6 · The paper itself

Abstract

Considerable advances have been made in the effort to prevent mother-to-child HIV transmission (PMTCT) in sub-Saharan Africa. Clinical trials have demonstrated the efficacy of antiretroviral regimens to interrupt HIV transmission through the antenatal, intrapartum, and postnatal periods. Scientific discoveries have been rapidly translated into health policy, bolstered by substantial investment in health infrastructure capable of delivering increasingly complex services. A new scientific agenda is also emerging, one that is focused on the challenges of effective and sustainable program implementation. Finally, global campaigns to "virtually eliminate" pediatric HIV and dramatically reduce HIV-related maternal mortality have mobilized new resources and renewed political will. Each of these developments marks a major step in regional PMTCT efforts; their convergence signals a time of rapid progress in the field, characterized by an increased interdependency between clinical research, program implementation, and policy. In this review, we take stock of recent advances across each of these areas, highlighting the challenges--and opportunities--of improving health services for HIV-infected mothers and their children across the region.

Indexed as

MothersAdultAfrica South of the SaharaAnti-HIV AgentsBreast FeedingChildChild, PreschoolFemaleHealth PolicyHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMaleMaternal-Child Health CentersAnti-HIV Agents

Identifiers

PMID23440538
PMCPMC3644371
OpenAlexW1965986965

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.