ArticleHSR proceedings in intensive care & cardiovascular anesthesia2012
Selective decontamination of the digestive tract: an update of the evidence.
Article in HSR proceedings in intensive care & cardiovascular anesthesia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- A review on antibiotic and non-antibiotic decolonization strategies of multidrug-resistant bacteria in the gastrointestinal tract.Infection · 2026Review
- [Modulation of the gut microbiome for the eradication of multidrug-resistant pathogens: current approaches and perspectives].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026Review
- Decolonizing the gut from multidrug-resistant bacteria: Current strategies and future perspectives.World journal of methodology · 2026Review
- Gastrointestinal dysfunction is associated with mortality in severe burn patients: a 10-year retrospective observational study from South China.Military Medical Research · 2022Observational
- An animal model of limitation of gut colonization by carbapenemase-producing Klebsiella pneumoniae using rifaximin.Scientific reports · 2022Article
- Enteral Vancomycin to Eliminate MRSA Carriership of the Digestive Tract in Critically Ill Patients.Antibiotics (Basel, Switzerland) · 2022Article
- Risk factors for transmission of carbapenem-resistant Enterobacterales to healthcare personnel gloves and gowns in the USA.The Journal of hospital infection · 2021Observational
- Eradication of Resistant and Susceptible Aerobic Gram-Negative Bacteria From the Digestive Tract in Critically Ill Patients; an Observational Cohort Study.Frontiers in microbiology · 2021Article
- Antibacterial and Antifungal Therapy for Patients with Acute Pancreatitis at High Risk of Pancreatogenic Sepsis (Review).Sovremennye tekhnologii v meditsine · 2020Review
- Management and prevention of drug resistant infections in burn patients.Expert review of anti-infective therapy · 2019Review
- The ecological effects of selective decontamination of the digestive tract (SDD) on antimicrobial resistance: a 21-year longitudinal single-centre study.Critical care (London, England) · 2019Observational
- Effect of dietary cellulose supplementation on gut barrier function and apoptosis in a murine model of endotoxemia.PloS one · 2019Article
- Antipathy against SDD is justified: We are not sure.Intensive care medicine · 2018Article
- Cost of treating ventilator-associated pneumonia post cardiac surgery in the National Health Service: Results from a propensity-matched cohort study.Journal of the Intensive Care Society · 2018Article
- The Gut as the Motor of Multiple Organ Dysfunction in Critical Illness.Critical care clinics · 2016Review
- A systematic review and meta-analysis of perioperative oral decontamination in patients undergoing major elective surgery.Perioperative medicine (London, England) · 2016Article
- Brazilian recommendations of mechanical ventilation 2013. Part I.Revista Brasileira de terapia intensivaReview
- Gut failure in critical care: old school versus new school.Annals of gastroenterologyReview
- Brazilian recommendations of mechanical ventilation 2013. Part I.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selective decontamination of the digestive tract has been proven to prevent severe infections and to reduce mortality in critically ill patients. Historical arguments against its use, like the development of bacterial resistance and the absence of influence on mortality, have not been confirmed. Recent clinical trials designed to evaluate these variables and meta-analyses showed remarkable reductions in the incidence of resistant bacteria and a significant beneficial effect on survival. This review will update the evidence on the efficacy of selective decontamination of the digestive tract, and the issue of emergence of resistance, using data from randomized controlled trials and meta-analyses.
Indexed as
Identifiers
23440328PMC3484923What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.