Evidence map›Paper›PMID 23440173›Full record

Trial reportJAMA internal medicine2013

Ask-Advise-Connect: a new approach to smoking treatment delivery in health care settings.

Jennifer Irvin Vidrine, Sanjay Shete, Yumei Cao, Anthony Greisinger, Penny Harmonson, Barry Sharp, Lyndsay Miles, Susan M Zbikowski, David W Wetter

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in JAMA internal medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07073898 (Population Health Management Approaches to Increase Lung Cancer Screening in Community Health Centers - UG3 Pilot Clinical Trial), which is not on this map. Cited by 157 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed, 8 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07073898 nacompletednot on this mapstarted 2025, after this paper: background citation

Population Health Management Approaches to Increase Lung Cancer Screening in Community Health Centers - UG3 Pilot Clinical Trial

TypeinterventionalSponsorUniversity of UtahRan2025 to 2026Enrolled65ConditionsLung CancerArmsRepeated Text Messages (TM+), Conversational Agent (CA), Educational Video, Proactive Patient Navigation (PPN), Reactive Patient Navigation (RPN)
3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 8 syntheses or guidelines pooled it, 263 citations in OpenAlex.

  1. A Systematic Review of Electronic Community Resource Referral Systems.American journal of preventive medicine · 2023
    Pooled it
  2. Proactive Referral to Behavioral Smoking Cessation Programs by Healthcare Staff: A Systematic Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Pooled it
  3. Strategies to improve smoking cessation rates in primary care.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Pooled it
  5. Telerheumatology: A Systematic Review.Arthritis care & research · 2017
    Pooled it
  6. System change interventions for smoking cessation.The Cochrane database of systematic reviews · 2017
    Pooled it
  7. Use of electronic health records to support smoking cessation.The Cochrane database of systematic reviews · 2014
    Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Engagement With Stop Smoking Services After Referral or Signposting: A Mixed-Methods Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Use of Theory-Driven Report Back to Promote Lung Cancer Risk Reduction.International journal of environmental research and public health · 2021
    Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jennifer Irvin VidrineDepartment of Health Disparities Research, The University of Texas MD Anderson Cancer Center, 1400 Pressler St, Unit 1440, Houston, TX 77030, USA. jirvinvidrine@mdanderson.org
Sanjay Shete
Yumei Cao
Anthony Greisinger
Penny Harmonson
Barry Sharp
Lyndsay Miles
Susan M Zbikowski
David W Wetter
The University of Texas MD Anderson Cancer Center · USAlere (United Kingdom) · GBTexas Department of State Health Services · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Kathrin Milbury · 1985 to 2026
$290.8M
NCI NIH HHS CA016672NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

importanceSeveral national health care-based smoking cessation initiatives have been recommended to facilitate the delivery of evidence-based treatments, such as quitline (telephone-based tobacco cessation services) assistance. The most notable examples are the 5 As (Ask, Advise, Assess, Assist, Arrange) and Ask. Advise. Refer. (AAR) programs. Unfortunately, rates of primary care referrals to quitlines are low, and most referred smokers fail to call for assistance.

objectiveTo evaluate a new approach--Ask-Advise-Connect (AAC)--designed to address barriers to linking smokers with treatment.

designA pair-matched, 2-treatment-arm, group-randomized design in 10 family practice clinics in a single metropolitan area. Five clinics were randomized to the AAC (intervention) and 5 to the AAR (control) conditions. In both conditions, clinic staff were trained to assess and record the smoking status of all patients at all visits in the electronic health record, and smokers were given brief advice to quit. In the AAC clinics, the names and telephone numbers of smokers who agreed to be connected were sent electronically to the quitline daily, and patients were called proactively by the quitline within 48 hours. In the AAR clinics, smokers were offered a quitline referral card and encouraged to call on their own. All data were collected from February 8 through December 27, 2011.

settingTen clinics in Houston, Texas.

participantsSmoking status assessments were completed for 42,277 patients; 2052 unique smokers were identified at AAC clinics, and 1611 smokers were identified at AAR clinics.

interventionsLinking smokers with quitline-delivered treatment.

main outcome measureImpact was based on the RE-AIM (Reach, Efficacy, Adoption, Implementation, and Maintenance) conceptual framework and defined as the proportion of all identified smokers who enrolled in treatment.

resultsIn the AAC clinics, 7.8% of all identified smokers enrolled in treatment vs 0.6% in the AAR clinics (t4 = 9.19 [P < .001]; odds ratio, 11.60 [95% CI, 5.53-24.32]), a 13-fold increase in the proportion of smokers enrolling in treatment. CONCLUSIONS AND RELEVANCE: The system changes implemented in the AAC approach could be adopted broadly by other health care systems and have tremendous potential to reduce tobacco-related morbidity and mortality.

Indexed as

CommunicationPatient ParticipationDelivery of Health CareElectronic Health RecordsFamily PracticeHumansProgram DevelopmentProgram EvaluationReferral and ConsultationSmokingSmoking CessationTelemedicineUnited States

Identifiers

PMID23440173
PMCPMC3858085
OpenAlexW2076909067

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.