ArticlePlant physiology2013
Jasmonate controls leaf growth by repressing cell proliferation and the onset of endoreduplication while maintaining a potential stand-by mode.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
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Who cites it
91 citing papers in PubMed, 223 citations in OpenAlex.
- Elicitation and scale-up of Bacopa saponin production by plant cell suspension culture in stirred tank bioreactor.Bioprocess and biosystems engineering · 2026Article
- Abiotic Stress Responses inPlants (Basel, Switzerland) · 2026Article
- Genetic characteristics and agronomic traits in leafy head Chinese cabbage breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Effect of Methyl Jasmonate on the Growth, Antioxidant Potential, and Phenolic Compound Synthesis ofBiology · 2026Article
- Phytochrome B integrates jasmonic acid and warm temperature signaling pathways to regulate cotyledon chloroplast development.Nature communications · 2026Article
- Long-term methyl jasmonate exposure triggers COI1-independent induction of myrosinasesFrontiers in plant science · 2026Article
- Growth regulation during early fruit development in apple (Malus × domestica Borkh.): a temporal event map of transcriptome and phytohormone changes.BMC plant biology · 2025Article
- Guardians of Water and Gas Exchange: Adaptive Dynamics of Stomatal Development and Patterning.Plants (Basel, Switzerland) · 2025Review
- Interactions Between the Transcription Factor BOL/DRNL/ESR2 and the Jasmonate Pathway.Plants (Basel, Switzerland) · 2025Article
- 3,5-DCQA as a Major Molecule in MeJA-TreatedBiomolecules · 2024Article
- Decrypting Molecular Mechanisms Involved in Counteracting Copper and Nickel Toxicity in Jack Pine (Plants (Basel, Switzerland) · 2024Article
- Identification of bZIP Transcription Factors That Regulate the Development of Leaf Epidermal Cells inInternational journal of molecular sciences · 2024Article
- AsHSP26.2, a creeping bentgrass chloroplast small heat shock protein positively regulates plant development.Plant cell reports · 2024Article
- Jasmonates, gibberellins, and powdery mildew modify cell cycle progression and evoke differential spatiotemporal responses along the barley leaf.Journal of experimental botany · 2024Article
- Overexpression of the ribosome-inactivating proteinFrontiers in plant science · 2024Article
- Genome-wide identification and expression analysis of the C2H2-zinc finger transcription factor gene family and screening of candidate genes involved in floral development inFrontiers in genetics · 2024Article
- High endoreduplication after drought-related conditions in haploid but not diploid mosses.Annals of botany · 2023Article
- Immunolocalization of Jasmonates and Auxins in Pea Roots in Connection with Inhibition of Root Growth under Salinity Conditions.International journal of molecular sciences · 2023Article
- Single-cell resolution analysis reveals the preparation for reprogramming the fate of stem cell niche in cotton lateral meristem.Genome biology · 2023Article
- Cytokinin Promotes Jasmonic Acid Accumulation in the Control of Maize Leaf Growth.Plants (Basel, Switzerland) · 2023Article
31 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
Phytohormones regulate plant growth from cell division to organ development. Jasmonates (JAs) are signaling molecules that have been implicated in stress-induced responses. However, they have also been shown to inhibit plant growth, but the mechanisms are not well understood. The effects of methyl jasmonate (MeJA) on leaf growth regulation were investigated in Arabidopsis (Arabidopsis thaliana) mutants altered in JA synthesis and perception, allene oxide synthase and coi1-16B (for coronatine insensitive1), respectively. We show that MeJA inhibits leaf growth through the JA receptor COI1 by reducing both cell number and size. Further investigations using flow cytometry analyses allowed us to evaluate ploidy levels and to monitor cell cycle progression in leaves and cotyledons of Arabidopsis and/or Nicotiana benthamiana at different stages of development. Additionally, a novel global transcription profiling analysis involving continuous treatment with MeJA was carried out to identify the molecular players whose expression is regulated during leaf development by this hormone and COI1. The results of these studies revealed that MeJA delays the switch from the mitotic cell cycle to the endoreduplication cycle, which accompanies cell expansion, in a COI1-dependent manner and inhibits the mitotic cycle itself, arresting cells in G1 phase prior to the S-phase transition. Significantly, we show that MeJA activates critical regulators of endoreduplication and affects the expression of key determinants of DNA replication. Our discoveries also suggest that MeJA may contribute to the maintenance of a cellular "stand-by mode" by keeping the expression of ribosomal genes at an elevated level. Finally, we propose a novel model for MeJA-regulated COI1-dependent leaf growth inhibition.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.