Evidence map›Paper›PMID 23439113›Full record

ArticleNeuron2013

Is instability good for the brain?

Robert A Carrillo, Kaushiki Menon, Kai Zinn

Abstract readComment
PubMed Publisher
In one paragraph

Article in Neuron, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Stability properties of neuronal microtubules.Cytoskeleton (Hoboken, N.J.) · 2016
    Review
  3. Cdk5 regulates developmental remodeling of mushroom body neurons in Drosophila.Developmental dynamics : an official publication of the American Association of Anatomists · 2015
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Robert A CarrilloBroad Center, Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.
Kaushiki Menon
Kai Zinn
California Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Neuron, Nahm et al. (2013) examine the Drosophila ortholog of spartin, the human gene mutated in a form of hereditary spastic paraplegia. Spartin inhibits BMP signaling and upregulation of BMP signaling may increase microtubule stability and neurodegeneration.

Indexed as

Bone Morphogenetic Protein ReceptorsBone Morphogenetic ProteinsBrainDrosophila ProteinsGene Expression Regulation, DevelopmentalHumansRadionuclide ImagingReceptors, Cell SurfaceSignal TransductionBone Morphogenetic Protein ReceptorsBone Morphogenetic ProteinsDrosophila ProteinsReceptors, Cell Surface

Identifiers

PMID23439113
OpenAlexW2004725571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.