ArticleNeuron2013
RANTing about C9orf72.
Article in Neuron, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Hippocampal sclerosis dementia with the C9ORF72 hexanucleotide repeat expansion.Neurobiology of aging · 2014Trial
- Multiple Roles of Transforming Growth Factor Beta in Amyotrophic Lateral Sclerosis.International journal of molecular sciences · 2020Review
- The Role of Sex and Sex Hormones in Neurodegenerative Diseases.Endocrine reviews · 2020Review
- A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases.Frontiers in aging neuroscience · 2020Article
- The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.Cell stress & chaperones · 2018Article
- Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.Autophagy · 2017Article
- The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.Frontiers in molecular neuroscience · 2017Review
- Repeat Associated Non-AUG Translation (RAN Translation) Dependent on Sequence Downstream of the ATXN2 CAG Repeat.PloS one · 2015Article
- C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia: gain or loss of function?Current opinion in neurology · 2014Review
- C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.Science (New York, N.Y.) · 2014Article
- C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies.Neurology · 2014Article
- Differential autophagy power in the spinal cord and muscle of transgenic ALS mice.Frontiers in cellular neuroscience · 2013Article
- Oligonucleotide-Based Therapy for FTD/ALS Caused by the C9orf72 Repeat Expansion: A Perspective.Journal of nucleic acids · 2013Review
Corrections and comments
- Comment on
Authors and funding
3 authors.
Funding
Abstract
A noncoding repeat expansion in the C9orf72 gene is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis. In this issue of Neuron, Ash et al. (2013) show that despite being noncoding the repeats are translated, leading to widespread neuronal aggregates of the translated proteins.
Indexed as
Identifiers
23439112What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.