Evidence map›Paper›PMID 23438304›Full record

ArticleDiabetes technology & therapeutics2013

Routine sensor-augmented pump therapy in type 1 diabetes: the INTERPRET study.

Kirsten Nørgaard, Andrea Scaramuzza, Natasa Bratina, Nebojsa M Lalić, Przemyslaw Jarosz-Chobot, Győző Kocsis, Edita Jasinskiene, Christophe De Block, Odile Carrette, Javier Castañeda and 2 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Diabetes technology & therapeutics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 107 citations in OpenAlex.

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  14. The Cost-Effectiveness of an Advanced Hybrid Closed-Loop System in People with Type 1 Diabetes: a Health Economic Analysis in Sweden.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021
    Article
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  16. Real-Life Management and Effectiveness of Insulin Pump with or Without Continuous Glucose Monitoring in Adults with Type 1 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 13 countries.

Kirsten NørgaardHvidovre University Hospital, Hvidovre, Denmark. Kirsten.noergaard@regionh.dk
Andrea Scaramuzza
Natasa Bratina
Nebojsa M Lalić
Przemyslaw Jarosz-Chobot
Győző Kocsis
Edita Jasinskiene
Christophe De Block
Odile Carrette
Javier Castañeda
Ohad Cohen
Interpret Study Group
Antwerp University Hospital · BEBakken Museum · USHvidovre Hospital · DKLithuanian University of Health Sciences · LTLjubljana University Medical Centre · SILuigi Sacco Hospital · ITMedical University of Silesia · PLMedtronic (Ireland) · IEPéterfy Sándor Utcai Kórház-Rendelőintézet és Baleseti Központ · HUSheba Medical Center · ILUniversity of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSensor-augmented pump (SAP) therapy can improve glycemic control, compared with multiple daily insulin injections or with insulin pump therapy alone, without increasing the risk of hypoglycemia. SUBJECTS AND

methodsA 12-month observational study in patients with type 1 diabetes treated with continuous subcutaneous insulin infusion (CSII), upon the introduction of continuous glucose monitoring (CGM), was conducted in 15 countries (in Europe and in Israel) to document the real-life use of SAP and assess which variables are associated with improvement in type 1 diabetes management.

resultsData from 263 patients (38% male; mean age, 28.0 ± 15.7 years [range, 1-69 years]; body mass index, 23.3 ± 4.9 kg/m(2); diabetes duration, 13.9 ± 10.7 years; CSII duration, 2.6 ± 3 years) were collected. Baseline mean glycated hemoglobin A1c (HbA1c) was 8.1 ± 1.4%; 82% had suboptimal HbA1c (≥ 7%). The average sensor use for 12 months was 30% (range, 0-94%), and sensor use decreased with time (first 3 months, 37%; last 3 months, 27%). Factors associated with improvement in HbA1c after 12 months in patients with baseline HbA1c ≥ 7% were high baseline HbA1c (P<0.001), older age group (P<0.001), and more frequent sensor use (P = 0.047). Significantly less hospitalization, increased treatment satisfaction, and reduced fear of hypoglycemia were reported after 12 months of SAP.

conclusionsThis is the largest and longest multicenter prospective observational study providing real-life data on SAP. These results are consistent with those of controlled trials showing the effectiveness of CGM in pump users.

Indexed as

Insulin Infusion SystemsAdolescentAdultAgedBiosensing TechniquesBlood GlucoseBody Mass IndexChildChild, PreschoolDiabetes Mellitus, Type 1EuropeFemaleGlycated HemoglobinHospitalizationHumansHypoglycemic AgentsBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic Agents

Identifiers

PMID23438304
PMCPMC3696941
OpenAlexW2031432201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.