ArticleChemical communications (Cambridge, England)2013
A potent antioxidant small molecule aimed at targeting metal-based oxidative stress in neurodegenerative disorders.
Article in Chemical communications (Cambridge, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 61 citations in OpenAlex.
- Antioxidant Potential of a Non-Heme Iron Complex: Mitigating HInorganic chemistry · 2026Article
- Simplified synthesis of anti-oxidant small moleculeMethodsX · 2026Article
- TargetingMetabolites · 2026Article
- Significant Activity of Pytren-2Q, a 2‑Quinoline Polyamine Compound, against High-Concern Human Pathogenic Fungi.ACS omega · 2026Article
- Predicting pRSC advances · 2025Article
- Hydrogen Peroxide Disproportionation Activity Is Sensitive to Pyridine Substitutions on Manganese Catalysts Derived from 12-Membered Tetra-Aza Macrocyclic Ligands.Inorganic chemistry · 2023Article
- Challenges and Opportunities of Metal Chelation Therapy in Trace Metals Overload-Induced Alzheimer's Disease.Neurotoxicity research · 2023Review
- Increased Efficiency of a Functional SOD Mimic Achieved with Pyridine Modification on a Pyclen-Based Copper(II) Complex.Inorganic chemistry · 2023Article
- Pyridine modifications regulate the electronics and reactivity of Fe-pyridinophane complexes.Dalton transactions (Cambridge, England : 2003) · 2023Article
- Estimation of the reducing power and electrochemical behavior of few flavonoids and polyhydroxybenzophenones substantiated by bond dissociation energy: a comparative analysis.Molecular diversity · 2022Article
- pH-dependent concatenation of an inorganic complex results in solid state helix formation.Inorganica chimica acta · 2022Article
- Assembly of Polyiodide Networks with Cu(II) Complexes of Pyridinol-Based Tetraaza Macrocycles.Inorganic chemistry · 2022Article
- A macrocyclic molecule with multiple antioxidative activities protects the lens from oxidative damage.Frontiers in chemistry · 2022Article
- Metals and Metal-Nanoparticles in Human Pathologies: From Exposure to Therapy.Molecules (Basel, Switzerland) · 2021Review
- Mechanistic Insights into Iron-Catalyzed C-H Bond Activation and C-C Coupling.Organometallics · 2021Article
- Protein Formulations Containing Polysorbates: Are Metal Chelators Needed at All?Antioxidants (Basel, Switzerland) · 2020Article
- Synthesis of 12-Membered Tetra-aza Macrocyclic Pyridinophanes Bearing Electron-Withdrawing Groups.The Journal of organic chemistry · 2020Article
- Electronic influence of substitution on the pyridine ring within NNN pincer-type molecules.Dalton transactions (Cambridge, England : 2003) · 2020Article
- Functionalized pyridine in pyclen-based iron(iii) complexes: evaluation of fundamental properties.RSC advances · 2020Article
- Enhancement of the Antioxidant Activity and Neurotherapeutic Features through Pyridol Addition to Tetraazamacrocyclic Molecules.Inorganic chemistry · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Metal-ion misregulation and oxidative stress have been linked to the progressive neurological decline associated with multiple neurodegenerative disorders. Transition metal-mediated oxidation of biomolecules via Fenton chemical reactions plays a role in disease progression. Herein we report the synthesis, characterization and antioxidant activity of 2; a pyclen derivative with enhanced antioxidant character.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.