Evidence map›Paper›PMID 23437102›Full record

ArticlePloS one2013

Comparison of age-stratified seroprevalence of antibodies against norovirus GII in India and the United Kingdom.

Vipin Kumar Menon, Santosh George, Farah Aladin, Sameena Nawaz, Rajiv Sarkar, Ben Lopman, James J Gray, Miren Iturriza Gomara, Gagandeep Kang

Abstract readComparative Study
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Norovirus in Latin America: Systematic Review and Meta-analysis.The Pediatric infectious disease journal · 2017
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vipin Kumar MenonDepartment of Gastrointestinal Sciences, Christian Medical College, Vellore, India.
Santosh George
Farah Aladin
Sameena Nawaz
Rajiv Sarkar
Ben Lopman
James J Gray
Miren Iturriza Gomara
Gagandeep Kang

Funding

Multi-disciplinary research training in enteric infectionsD43TW007392 · FIC · CHRISTIAN MEDICAL COLLEGE · PI KANG, GAGANDEEP · 2005 to 2020
$2.9M
FIC NIH HHS D43 TW007392
6 · The paper itself

Abstract

Noroviruses are a common cause of gastroenteritis worldwide, but outbreaks appear to be more common in industrialized countries than in developing countries, possibly reflecting differences in exposure and immunity. In this study, age-stratified sera from India and UK populations were analysed for the presence of norovirus-genogroup II specific IgG by a time resolved immunofluorescence assay and relative levels of antibodies in the two populations were compared. Antibody levels were higher among all age groups in India than in UK and increased with age in India, whereas in the UK, levels of antibody decreased in adulthood. These results indicate different patterns of exposure to noroviruses in the two countries.

Indexed as

AdolescentAdultAge DistributionAntibodies, ViralCaliciviridae InfectionsChildChild, PreschoolCohort StudiesEuropiumGastroenteritisHumansIndiaInfantInfant, NewbornNorovirusSeroepidemiologic StudiesAntibodies, ViralEuropium

Identifiers

PMID23437102
PMCPMC3578856

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.