ArticlePloS one2013
Interfamily transfer of dual NB-LRR genes confers resistance to multiple pathogens.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 101 citations in OpenAlex.
- Two genes, one switch: a bidirectional promoter strategy for inducible plant immunity.Plant physiology · 2026Article
- Genome-wide association study of exotic Fragaria germplasm accessions for resistance to Phytophthora crown rot in strawberry.BMC plant biology · 2026Article
- Expression of a modified Avr3a gene under the control of a synthetic pathogen-inducible promoter leads to Phytophthora infestans resistance in potato.Plant biotechnology journal · 2025Article
- Complete Genome of Rose Myrtle,Plants (Basel, Switzerland) · 2023Article
- Engineering plant immune circuit: walking to the bright future with a novel toolbox.Plant biotechnology journal · 2023Review
- From prediction to function: Current practices and challenges towards the functional characterization of type III effectors.Frontiers in microbiology · 2023Review
- A high-quality pseudo-phased genome for Melaleuca quinquenervia shows allelic diversity of NLR-type resistance genes.GigaScience · 2022Article
- Identification of RipAZ1 as an avirulence determinant of Ralstonia solanacearum in Solanum americanum.Molecular plant pathology · 2021Article
- The wheat Sr22, Sr33, Sr35 and Sr45 genes confer resistance against stem rust in barley.Plant biotechnology journal · 2021Article
- The ConservedFrontiers in microbiology · 2021Article
- Cherry picking by pseudomonads: After a century of research on canker, genomics provides insights into the evolution of pathogenicity towards stone fruits.Plant pathology · 2020Review
- A method of transformation and current progress in transgenic research on cucumbers andPlant biotechnology (Tokyo, Japan) · 2020Article
- Plant NLRs: The Whistleblowers of Plant Immunity.Plant communications · 2020Review
- Article
- Next-generation sequencing identified genomic region and diagnostic markers for resistance to bacterial wilt on chromosome B02 in peanut (Arachis hypogaea L.).Plant biotechnology journal · 2019Article
- Calcium-signaling proteins mediate the plant transcriptomic response during a well-establishedHorticulture research · 2019Article
- Recent advances in developing disease resistance in plants.F1000Research · 2019Review
- Overexpression ofFrontiers in plant science · 2019Article
- Pyramiding of transgenic Pm3 alleles in wheat results in improved powdery mildew resistance in the field.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- High throughput transcriptome analysis of coffee reveals prehaustorial resistance in response to Hemileia vastatrix infection.Plant molecular biology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A major class of disease resistance (R) genes which encode nucleotide binding and leucine rich repeat (NB-LRR) proteins have been used in traditional breeding programs for crop protection. However, it has been difficult to functionally transfer NB-LRR-type R genes in taxonomically distinct families. Here we demonstrate that a pair of Arabidopsis (Brassicaceae) NB-LRR-type R genes, RPS4 and RRS1, properly function in two other Brassicaceae, Brassica rapa and Brassica napus, but also in two Solanaceae, Nicotiana benthamiana and tomato (Solanum lycopersicum). The solanaceous plants transformed with RPS4/RRS1 confer bacterial effector-specific immunity responses. Furthermore, RPS4 and RRS1, which confer resistance to a fungal pathogen Colletotrichum higginsianum in Brassicaceae, also protect against Colletotrichum orbiculare in cucumber (Cucurbitaceae). Importantly, RPS4/RRS1 transgenic plants show no autoimmune phenotypes, indicating that the NB-LRR proteins are tightly regulated. The successful transfer of two R genes at the family level implies that the downstream components of R genes are highly conserved. The functional interfamily transfer of R genes can be a powerful strategy for providing resistance to a broad range of pathogens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.