ReviewInternal and emergency medicine2013
Thyroid hormone and cardiovascular system: from basic concepts to clinical application.
Review in Internal and emergency medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- The Value of Decreased Thyroid Hormone for Predicting Mortality in Adult Septic Patients: A Systematic Review and Meta-Analysis.Scientific reports · 2018Pooled it
- Association of caspase-3 with thyroid hormone levels in patients with hypothyroidism - A hospital-based study.EJIFCC · 2026Article
- Prognostic significance of thyroid hormone T3 in patients with septic shock: a retrospective cohort study.PeerJ · 2023Article
- The Utilization of Chinese Herbal Products for Hyperthyroidism in National Health Insurance System (NHIRD) of Taiwan: A Population-Based Study.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Nonthyroidal Illness Syndrome: To Treat or Not to Treat? Have We Answered the Question? A Review of Metanalyses.Frontiers in endocrinology · 2022Review
- Thyroid hormone disorders: a predictor of mortality in patients with septic shock defined by Sepsis-3?Internal and emergency medicine · 2021Observational
- Rabbit thyroid extracellular matrix as a 3D bioscaffold for thyroid bioengineering: a preliminary in vitro study.Biomedical engineering online · 2021Article
- Effect of repetitive potassium iodide on thyroid and cardiovascular functions in elderly rats.Biochemistry and biophysics reports · 2020Article
- The impact of thyroid hormone dysfunction on ischemic heart disease.Endocrine connections · 2019Review
- Plasma endothelin-1 levels are increased in atrial fibrillation patients with hyperthyroidism.PloS one · 2018Article
- Myocardium of patients with dilated cardiomyopathy presents altered expression of genes involved in thyroid hormone biosynthesis.PloS one · 2018Article
- In vivo dissolution of levothyroxine soft gel capsules.Internal and emergency medicine · 2016Article
- MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo.Journal of molecular endocrinology · 2016Article
- Role of thyroid hormones in ventricular remodeling.Current heart failure reports · 2015Review
- Functional thyrotropin receptor expression in the ventricle and the effects on ventricular BNP secretion.Endocrine · 2014Article
- Article
- Levothyroxine improves Paraoxonase (PON-1) serum levels in patients with primary hypothyroidism: Case-control study.Journal of advanced pharmaceutical technology & researchArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Experimental and clinical findings strongly support the concept that thyroid hormone (TH) plays a fundamental role in the cardiovascular (CV) homeostasis. CV diseases represent a major public health care and economic problem being one of the principal causes of morbidity, mortality and hospitalization. In particular, chronic heart failure (HF) is one of the most common reasons for general practitioners consultations in people >65-70 years old. TH derangement may have a key role in the evolution process of HF. In HF, the main and earlier alteration of the thyroid function is referred to as "low-T3" syndrome characterized by the reduction in serum total T3 and free T3 with normal levels of thyroxine (T4) and thyrotropin (TSH). This syndrome may affect till one-third of advanced HF patients. The main goal of this mini-review is to examine the main pathophysiological and clinical links between an altered thyroid metabolism and CV diseases, namely HF during progression of disease from organ specific to systemic disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.