ReviewSurgery today2013
Mixed corticomedullary adrenal carcinoma.
Review in Surgery today, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Adrenal mixed corticomedullary tumors: report of a case with molecular characterization and systematic review.Virchows Archiv : an international journal of pathology · 2026Pooled it
- Mixed Corticomedullary Tumor of the Adrenal Gland: A Case Report and Literature Review.Medicina (Kaunas, Lithuania) · 2023Review
- Current Understanding of "Mixed Corticomedullary Adrenal Tumor" and an Insight into Genomic Profiling.Clinics and practice · 2022Review
- Mixed corticomedullary tumor of the adrenal gland.Frontiers in endocrinology · 2022Review
- Mixed Corticomedullary Tumor Accompanied by Unilateral Aldosterone-Producing Adrenocortical Micronodules: a Case Report.Journal of the Endocrine Society · 2021Article
- Adrenal Corticomedullary Mixed Tumor Associated With theJournal of the Endocrine Society · 2020Article
- CT and MRI of adrenal gland pathologies.Quantitative imaging in medicine and surgery · 2018Review
- Corticomedullary mixed tumour resembling a small adrenal gland-involvement of cancer stem cells: case report.BMC endocrine disorders · 2017Article
- Mixed corticomedullary adrenal carcinoma - case report: Comparison in features, treatment and prognosis with the other two reported cases.International journal of surgery case reports · 2017Article
- Adrenal Cushing syndrome with detectable ACTH from an unexpected source.BMJ case reports · 2016Article
- Malignant Perivascular Epithelioid Cell Tumor (PEComa) of the Adrenal Gland: Report of a Rare Case Posing Diagnostic Challenge with the Role of Immunohistochemistry in the Diagnosis.Endocrine pathology · 2015Article
- A functioning adrenal adenoma and pheochromocytoma in the same adrenal gland: two discrete adrenal incidentalomas.The Korean journal of internal medicine · 2015Article
- Corticomedullary Mixed Tumor of the Adrenal Gland with ApparentIndian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Truly mixed corticomedullary tumors (MCMTs) are extremely rare and present as a single tumor mass composed of an intimately admixed population of both adrenal cortical cells and pheochromocytes. The current study describes the first case of a mixed corticomedullary adrenal carcinoma. In addition, we also review the published data on MCMTs to determine their clinical features, biochemical characteristics, pathological findings, and management. In order to compose this review, a search of the international literature for MCMTs was conducted. Fifteen related articles were found. The clinical and pathological information was obtained for all reported cases. MCMTs were found almost exclusively in females. In the vast majority of patients, the symptoms were related to the tumor's hormone hypersecretion. Hypertension and diabetes were present in 80 and 40 % of cases, respectively. Cushing's syndrome was reported in eight cases (53.33 %). A final diagnosis was made in all cases after surgery based on the pathological results. As of the writing of this article, all published cases of MCMTs had benign clinical behavior, with no instances of metastasis or death due to the tumor. MCMTs are currently considered to be benign tumors. Ours is the first case of malignant MCMT reported in the literature. The potential for malignancy should therefore be considered for these tumors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.