Evidence map›Paper›PMID 23435377›Full record

ReviewCancer letters2013

Bioavailability of phytochemicals and its enhancement by drug delivery systems.

Farrukh Aqil, Radha Munagala, Jeyaprakash Jeyabalan, Manicka V Vadhanam

Abstract readReview
In one paragraph

Review in Cancer letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed.

  1. Trial
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  7. HJournal of nanobiotechnology · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Insights into dietary supplements as popular product supporting the diet.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  13. Review
  14. Article
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  16. Review
  17. Review
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  19. Article
  20. Review

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Farrukh AqilJames Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, United States.
Radha MunagalaJames Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, United States.
Jeyaprakash JeyabalanJames Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, United States.
Manicka V VadhanamJames Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, United States. Electronic address: mvvadh01@louisville.edu.

Funding

Identification and synergism of bioactive components of pomegranate juice in prosR21CA143676 · NCI · UNIVERSITY OF LOUISVILLE · PI VADHANAM, MANICKA V · 2010 to 2011
$352k
NCI NIH HHS CA-143676NCI NIH HHS R21 CA143676
6 · The paper itself

Abstract

Issues of poor oral bioavailability of cancer chemopreventives have hindered progress in cancer prevention. Novel delivery systems that modulate the pharmacokinetics of existing drugs, such as nanoparticles, cyclodextrins, niosomes, liposomes and implants, could be used to enhance the delivery of chemopreventive agents to target sites. The development of new approaches in prevention and treatment of cancer could encompass new delivery systems for approved and newly investigated compounds. In this review, we discuss some of the delivery approaches that have already made an impact by either delivering a drug to target tissue or increasing its bioavailability by many fold.

Indexed as

Anticarcinogenic AgentsBiological AvailabilityCyclodextrinsDrug Delivery SystemsHumansLiposomesMicellesNanoparticlesPhytochemicalsAnticarcinogenic AgentsCyclodextrinsLiposomesMicellesPhytochemicals

Identifiers

PMID23435377
PMCPMC3815990

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.