Evidence map›Paper›PMID 23435351›Full record

ReviewSeminars in cell & developmental biology2013

Global approaches for telling time: omics and the Arabidopsis circadian clock.

Brenda Y Chow, Steve A Kay

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Brenda Y ChowSection of Cell and Developmental Biology and Center for Chronobiology, Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, United States. bchow@ucsd.edu
Steve A Kay
University of California, San Diego · USUniversity of Southern California · US

Funding

ENZYMOLOGY OF MISMATCH REPAIR IN YEASTR01GM050006 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard D Kolodner · 1994 to 2026
$10.5M
GENETIC ANALYSIS OF CIRCADIAN RHYTHMS IN ARABIDOPSISR01GM056006 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAY, STEVE A, PRUNEDA-PAZ, JOSE L · 1996 to 2016
$6.0M
Molecular Mechanisms in the Arabidopsis Circadian ClockR01GM067837 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAY, STEVE A · 2003 to 2015
$4.7M
Molecular Mechanisms in the Arabidopsis Circadian ClockR37GM067837 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI STEVE A KAY · 2017 to 2026
$4.4M
NIGMS NIH HHS GM67837NIGMS NIH HHS R01 GM050006NIGMS NIH HHS R01 GM056006NIGMS NIH HHS R01 GM067837NIGMS NIH HHS R01 GM50006NIGMS NIH HHS R37 GM067837
6 · The paper itself

Abstract

The circadian clock is an endogenous timer that anticipates and synchronizes biological processes to the environment. Traditional genetic approaches identified the underlying principles and genetic components, but new discoveries have been greatly impeded by the embedded redundancies that confer necessary robustness to the clock architecture. To overcome this, global (omic) techniques have provided a new depth of information about the Arabidopsis clock. Our understanding of the factors, regulation, and mechanistic connectivity between clock genes and with output processes has substantially broadened through genomic (cDNA libraries, yeast one-hybrid, protein binding microarrays, and ChIP-seq), transcriptomic (microarrays, RNA-seq), proteomic (mass spectrometry and chemical libraries), and metabolomic (mass spectrometry) approaches. This evolution in research will undoubtedly enhance our understanding of how the circadian clock optimizes growth and fitness.

Indexed as

Gene Expression Regulation, PlantArabidopsisArabidopsis ProteinsCircadian ClocksCircadian RhythmGene LibraryOligonucleotide Array Sequence AnalysisProtein Array AnalysisProtein Interaction MappingProteomicsTranscription FactorsTranscription, GeneticArabidopsis ProteinsTranscription Factors

Identifiers

PMID23435351
PMCPMC3759395
OpenAlexW1997904943

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.