Evidence map›Paper›PMID 23435123›Full record

ArticleJournal of structural biology2013

Marker-free dual-axis tilt series alignment.

Hanspeter Winkler, Kenneth A Taylor

Abstract read
In one paragraph

Article in Journal of structural biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Quantitative Cryo-Electron Tomography.Frontiers in molecular biosciences · 2022
    Review
  2. Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hanspeter WinklerFlorida State University, Institute of Molecular Biophysics, Tallahassee, FL 32306, USA. winkler@sb.fsu.edu
Kenneth A Taylor

Funding

EM STUDIES ON MUSCLER01GM030598 · NIGMS · FLORIDA STATE UNIVERSITY · PI TAYLOR, KENNETH ALLEN · 1985 to 2020
$4.9M
Computational methods for molecular tomographyR01GM082948 · NIGMS · FLORIDA STATE UNIVERSITY · PI WINKLER, HANSPETER · 2007 to 2011
$1.3M
NIGMS NIH HHS GM0829 48NIGMS NIH HHS GM3059NIGMS NIH HHS R01 GM030598NIGMS NIH HHS R01 GM082948
6 · The paper itself

Abstract

Dual-axis tilt series in electron tomography are collected by successively tilting the object about two approximately orthogonal tilt axes. Here we report on the extension of marker-free image registration based on cross-correlation techniques to dual-axis tilt series. A simultaneous geometry refinement yields accurate parameters for the computation of the final reconstruction. Both, image registration and 3D-reconstruction operate on the combined data from the paired single axis series rather than computing individual single axis tomograms followed by a separate combination step. We show that with simultaneous registration and reconstruction of dual-axis tilt series, tomograms with higher resolution are obtained than by merging separately computed tomograms.

Indexed as

Molecular ConformationSoftwareElectron Microscope TomographyImage Processing, Computer-Assisted

Identifiers

PMID23435123
PMCPMC4098971

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.