Trial reportMenopause (New York, N.Y.)2013
Clinical hypnosis in the treatment of postmenopausal hot flashes: a randomized controlled trial.
Trial report in Menopause (New York, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02187419 (Hypnosis to Improve Sleep in Menopause), which is not on this map. Cited by 45 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hypnosis to Improve Sleep in Menopause: Determination of Optimal Dose and Method
Who cites it
45 citing papers in PubMed, 4 syntheses or guidelines pooled it, 182 citations in OpenAlex.
- Magnitude of placebo response in clinical trials of paroxetine for vasomotor symptoms: a meta-analysis.Frontiers in psychiatry · 2023Pooled it
- Variation in menopausal vasomotor symptoms outcomes in clinical trials: a systematic review.BJOG : an international journal of obstetrics and gynaecology · 2020Pooled it
- Hypnosis Intervention Effects on Sleep Outcomes: A Systematic Review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018Pooled it
- Effects of non-pharmacological supportive care for hot flushes in breast cancer: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Pooled it
- Self-Administered Hypnosis vs Sham Hypnosis for Hot Flashes: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Effect of Hypnosis on Anxiety: Results from a Randomized Controlled Trial with Women in Postmenopause.Journal of clinical psychology in medical settings · 2021Trial
- Open-label placebos for menopausal hot flushes: a randomized controlled trial.Scientific reports · 2020Trial
- Self-Hypnosis for Sleep Disturbances in Menopausal Women.Journal of women's health (2002) · 2020Trial
- Hypnotherapy to Reduce Hot Flashes: Examination of Response Expectancies as a Mediator of Outcomes.Journal of evidence-based complementary & alternative medicine · 2017Trial
- Efficacy of a biobehavioral intervention for hot flashes: a randomized controlled pilot study.Menopause (New York, N.Y.) · 2017Trial
- Hypnosis Intervention for Sleep Disturbances in Individuals with Mild Cognitive Impairment: A Randomized Pilot Study.The International journal of clinical and experimental hypnosisTrial
- Hypnosis Intervention for Sleep Disturbance: Determination of Optimal Dose and Method of Delivery for Postmenopausal Women.The International journal of clinical and experimental hypnosisTrial
- [Perimenopause and postmenopause: acute diagnostic and therapeutic aspects for the DACH region : Consensus paper of the Austrian Society for Gynecology and Obstetrics (OEGGG), the German Society for Gynecology and Obstetrics (DGGG), the German Menopause Society (DMG) and the Swiss Society for Gynecology and Obstetrics (SGGG)].Wiener klinische Wochenschrift · 2026Article
- Risk factors, management and consequences of severe menopausal vasomotor symptoms.Nature reviews. Endocrinology · 2026Review
- Potential for Harm in the Treatment of Pediatric Obsessive-Compulsive Disorder: Pitfalls and Best Practices.Research on child and adolescent psychopathology · 2025Review
- Management of menopausal hot flushes. Recommendations from the Spanish Menopause Society.European journal of obstetrics & gynecology and reproductive biology: X · 2025Review
- Management of vasomotor symptoms in cancer patients.The oncologist · 2025Review
- User Outcomes for an App-Delivered Hypnosis Intervention for Menopausal Hot Flashes: Retrospective Analysis.JMIR formative research · 2025Article
- Clinical Hypnosis and Cognitive Behavioral Therapy for Hot Flashes: A Scoping Review.Women's health reports (New Rochelle, N.Y.) · 2025Review
- Treating Hot Flashes with Hypnosis: Does Hypnotizability Modulate Reductions?Journal of clinical psychology in medical settings · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe use of estrogen and progesterone to manage vasomotor symptoms (ie, hot flashes and night sweats) has declined because of concerns about their risks, and there is an increased interest in alternate, effective, and low-risk treatments. This study reports the results of a randomized controlled trial of clinical hypnosis for treating vasomotor symptoms among postmenopausal women.
methodsThis is a randomized, single-blind, controlled, clinical trial involving 187 postmenopausal women reporting a minimum of seven hot flashes per day (or at least 50 hot flashes a week) at baseline between December 2008 and April 2012. Eligible participants received five weekly sessions of either clinical hypnosis or structured-attention control. Primary outcomes were hot flash frequency (subjectively and physiologically recorded) and hot flash score assessed by daily diaries on weeks 2 to 6 and week 12. Secondary outcomes included measures of hot flash-related daily interference, sleep quality, and treatment satisfaction.
resultsIn a modified intent-to-treat analysis that included all randomized participants who provided data, reported subjective hot flash frequency from baseline to week 12 showed a mean reduction of 55.82 (74.16%) hot flashes for the clinical hypnosis intervention versus a mean reduction of 12.89 (17.13%) hot flashes for controls (P < 0.001; 95% CI, 36.15-49.67). The mean reduction in hot flash score was 18.83 (80.32%) for the clinical hypnosis intervention as compared with 3.53 (15.38%) for controls (P < 0.001; 95% CI, 12.60-17.54). At 12-week follow-up, the mean reduction in physiologically monitored hot flashes was 5.92 (56.86%) for clinical hypnosis and 0.88 (9.94%) for controls (P < 0.001; 95% CI, 2.00-5.46). Secondary outcomes were significantly improved compared with controls at 12-week follow-up: hot flash-related interference (P < 0.001; 95% CI, 2.74-4.02), sleep quality (P < 0.001; 95% CI, 3.65-5.84), and treatment satisfaction (P < 0.001; 95% CI, 7.79-8.59).
conclusionsCompared with structured-attention control, clinical hypnosis results in significant reductions in self-reported and physiologically measured hot flashes and hot flash scores in postmenopausal women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.