ArticleMolecules (Basel, Switzerland)2013
New spiral γ-lactone enantiomers from the plant endophytic fungus Pestalotiopsis foedan.
Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Two new species ofMycoKeys · 2025Article
- Review
- Exploring Structural Diversity of Microbe Secondary Metabolites Using OSMAC Strategy: A Literature Review.Frontiers in microbiology · 2019Review
- Metabolites from the Paracel Islands Soft CoralMarine drugs · 2018Article
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2 authors.
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Abstract
(-)-(4S, 8S)-Foedanolide (1a) and (+)-(4R, 8R)-foedanolide (1b), a pair of new spiro-γ-lactone enantiomers, were isolated from the fermentation broth of the plant endophytic fungus Pestalotiopsis foedan by HPLC using a chiral column, achieving over 7% ee. Their structures and absolute configurations were determined on the basis of extensive analysis of NMR spectra combined with computational methods via calculation of the electronic circular dichroism (ECD) and optical rotation (OR). Compounds 1a and 1b showed moderate activities against HeLa, A-549, U-251, HepG2 and MCF-7 tumor cell lines.
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