ArticleInternational journal of molecular sciences2013
Production of pharmaceutical proteins in solanaceae food crops.
Article in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Hairy root culture: a potent method for improved secondary metabolite production of Solanaceous plants.Frontiers in plant science · 2023Review
- Two different domain architectures generate structural and functional diversity amongFrontiers in plant science · 2022Article
- Optimising expression and extraction of recombinant proteins in plants.Frontiers in plant science · 2022Review
- Medicinal Plants ofJournal of tropical medicine · 2022Review
- Overexpression of the recombinant human interferon-beta (Biotechnologia · 2021Article
- Bioproduction of a Therapeutic Vaccine Against Human Papillomavirus in Tomato Hairy Root Cultures.Frontiers in plant science · 2019Article
- Abnormal development of floral meristem triggers defective morphogenesis of generative system in transgenic tomatoes.Protoplasma · 2018Article
- Targeted gene disruption coupled with metabolic screen approach to uncover the LEAFY COTYLEDON1-LIKE4 (L1L4) function in tomato fruit metabolism.Plant cell reports · 2017Article
- Polyphenolic extract of InsP 5-ptase expressing tomato plants reduce the proliferation of MCF-7 breast cancer cells.PloS one · 2017Article
- Tobacco drought stress responses reveal new targets for Solanaceae crop improvement.BMC genomics · 2015Article
- Purification, identification and preliminary crystallographic studies of an allergenic protein from Solanum melongena.Acta crystallographica. Section F, Structural biology communications · 2015Article
- Recent developments in therapeutic protein expression technologies in plants.Biotechnology letters · 2015Review
- In silico study of binding motifs in squalene synthase enzyme of secondary metabolic pathway of solanaceae [corrected].Molecular biology reports · 2014Article
- Resistance to Botrytis cinerea in Solanum lycopersicoides involves widespread transcriptional reprogramming.BMC genomics · 2014Article
- Enhancing the health-promoting effects of tomato fruit for biofortified food.Mediators of inflammation · 2014Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The benefits of increased safety and cost-effectiveness make vegetable crops appropriate systems for the production and delivery of pharmaceutical proteins. In particular, Solanaceae edible crops could be inexpensive biofactories for oral vaccines and other pharmaceutical proteins that can be ingested as minimally processed extracts or as partially purified products. The field of crop plant biotechnology is advancing rapidly due to novel developments in genetic and genomic tools being made available today for the scientific community. In this review, we briefly summarize data now available regarding genomic resources for the Solanaceae family. In addition, we describe novel strategies developed for the expression of foreign proteins in vegetable crops and the utilization of these techniques to manufacture pharmaceutical proteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.